Results 121 to 130 of about 4,071,168 (281)

ODCalibrator: An Interactive Visualization System for OD Traffic Flow Calibration in Microscopic Traffic Simulations

Applied Sciences
Traffic simulation is essential for evaluating transportation policies, infrastructure changes, and mixed traffic scenarios with human-driven and autonomous vehicles, yet its reliability critically depends on accurate calibration of origin–destination ...
Jae-Won Jeon, DongHwa Shin, Ho-Chul Park
doaj   +1 more source

A hybrid numerical method for a microscopic and macroscopic traffic flow model

CoRR
In this paper, we introduce a traffic flow model based on a microscopic follow-the-leader model, while enforcing maximal constraints on the density and velocity of the flow. The related macroscopic model can be represented in conservative formulation.
Yuanhong Wu, Shuzhi Liu, Qinglong Zhang
openaire   +2 more sources

Pre‐Regenerative Endothelial Cells Empowered by Antler Blood Exosomes Orchestrate Peripheral Nerve Repair

Advanced Science, EarlyView.
The pre‐regenerative vascular niche (PVN) is essential for nerve repair, yet its endothelial blueprint remains unclear. We identified angiogenic ECs (AECs) as the dominant pre‐regenerative subset and found that antler blood–derived exosomes (AB‐EXO) promote repair via IMP3.
Jinsheng Huang, Qiang Chen, Aihua Jin, Xiaoqi Yang, Hui Zhou, Weiquan Gong, Jin Cheng, Jun Dai, Minjin Wang, Meihua Piao, Yuanyi Wang, Nan Zhou   +11 more
wiley   +1 more source

Agent Based Traffic Signals Regulating Flow On a Basic Grid [PDF]

, 2003
A simulation study on traffic light optimisation with agent-based behaviour of the traffic ...
Brockfeld, Elmar, Wagner, Peter, Mikat, Jürgen   +2 more
core  

Chiral Nanoparticles Suppress Inflammatory Infiltration to Promote Extracellular Matrix Remodeling for Ectopia Lentis Therapy

Advanced Science, EarlyView.
L‐cysteine‐configured chiral polyurethane nanoparticles suppress ocular inflammation and reduce extracellular matrix (ECM) degradation in ectopia lentis by regulating macrophages polarization and inhibiting nuclear factor kappa B signaling pathway. By promoting zonular fiber‐associated protein restoration and tissue repair, this minimally invasive ...
Yinuo Wen, Yan Yang, Haihan Gao, Yan Liu, Xinyue Wang, Linghao Song, Ruohong Li, Ao Miao, Jie Xu, Zhennan Zhao, Dan Li, Shenjie Peng, Linzhao Li, Min Zhang, Yonghang Liu, Liren Wang, Tianhui Chen, Yongxiang Jiang   +17 more
wiley   +1 more source

Microglial Deubiquitinase OTUD7B Stabilizes STAT3 to Promote Neuroinflammation and Cognitive Decline in Alzheimer's Disease

Advanced Science, EarlyView.
. ABSTRACT Neuroinflammation driven by microglial activation is a defining feature of Alzheimer's disease (AD), yet the molecular mechanisms sustaining this proinflammatory state remain unclear. Here, we identify the deubiquitinase OTUD7B as a critical regulator of microglial activation and AD pathology.
Luyao Li, Hao Tang, Qin Yu, Yuyang Zhang, Binglu Shi, Ying Kong, Leiyu Xu, Jingjing Shao, Chenghong Hu, Lingyu She, Zhe Wang, Haiyi Chen, Aleksandr V. Samorodov, Gang Cao, Xia Zhao, Yi Wang   +15 more
wiley   +1 more source

Coupled microscopic modelling of traffic demand and traffic flow on a city level [PDF]

, 2016
Microscopic models of traffic demand and traffic flow have reached a maturity which allows their usage for investigating large-scale effects of measures and/or developments. In microscopic models, every participant is described individually by a set of attributes.
Krajzewicz, Daniel, Cyganski, Rita, Heinrichs, Matthias, Erdmann, Jakob   +3 more
openaire   +1 more source

Evaluation of Impacts of Adaptive Cruise Control on Mixed Traffic Flow [PDF]

This paper addresses the impacts of Adaptive (Intelligent) Cruise Control (ACC) laws on traffic flow. Semi-automated vehicles, such as ACC Vehicles, with the capability to automatically follow each other in the same lane, will coexist with manually ...
Xi Zou, David Levinson
core  

TOLLIP Inhibits Psoriasis Progression via Suppressing PKM2‐Mediated Glycolysis in Keratinocytes

Advanced Science, EarlyView.
In this study, we identify TOLLIP as a critical regulator of psoriasis pathogenesis through its modulation of glycolytic metabolism. Our findings establish the TOLLIP‐PKM2‐glycolysis axis as a key mechanism linking metabolic reprogramming to psoriasis pathogenesis, and propose TOLLIP as a promising therapeutic target.
Xiuhuan Jiang, Guoying Miao, Na Shen, Qingxia Han, Xiaoru Han, Zichang Qiao, Kexin Feng, Zhuo Tan, Yaguang Wang, Xiuhua Liu, Chen Wu, Zhenzhen Yan   +11 more
wiley   +1 more source

Space-time modeling of traffic flow [PDF]

A key concern in transportation planning and traffic management is the ability to forecast traffic flows on a street network. Traffic flows forecasts can be transformed to obtain travel time estimates and then use these as input to travel demand models ...
Prastacos, Poulicos, Kamarianakis, Yiannis   +1 more
core