Results 101 to 110 of about 9,158 (291)

Lymphoid‐Tissue‐on‐Chip Recapitulates Human Antibody Responses In Vitro

Advanced Science, EarlyView.
The presented lymphoid‐tissue‐on‐chip system allows culture of primary human tonsil cells at organotypic high density under perfusion for up to 4 weeks, emulates immune response to soluble vaccines and vaccination via peripheral antigen‐presenting cells and represents a useful tool to assess cellular interactions during homeostasis, immune responses ...
Claudia Teufel, Anna‐Sophie Schlemmer, Andrea W. Eiken, Zachary W. Wagoner, Dennis Vöhringer, Lena Christ, Alex Dulovic, Patrick Marsall, Madeleine Fandrich, Eduardo J. S. Brás, Julia Marzi, Friederike Bärhold, Julia Philipp, Sven Becker, Lisa E. Wagar, Peter Loskill   +15 more
wiley   +1 more source

Bicycle as a traffic mode: From microscopic cycling behavior to macroscopic bicycle flow

Journal of Cycling and Micromobility Research
Cities allocate dedicated road space to bicycles in favor of active-mode road users. For urban environments with a mass bicycle volume, bicycle traffic congestion is likely to occur.
Ying-Chuan Ni, Michail A. Makridis, Anastasios Kouvelas   +2 more
doaj   +1 more source

The applicability of Catastrophe Theory to Microscopic Traffic Flow variables

, 2012
109 σ.Η κυκλοφοριακή συμφόρηση έχει αναλυθεί από πολλές οπτικές γωνίες και με διάφορα πρακτικά και θεωρητικά εργαλεία. Η κανονικοποίηση της κυκλοφορίας όμως παραμένει ένα από τα μεγάλα ζητήματα της κυκλοφοριακής ανάλυσης κυρίως γιατί η μετάβαση από τη ...
Παπαχαραλάμπους, Αλέξανδρος Ε., Papacharalampous, Alexandros E.   +1 more
core   +1 more source

Natural Variation of NAR5 Determines Nitrogenase Activity and the Yield in Soybean

Advanced Science, EarlyView.
This study identified NAR5, a gene encoding a subtilisin‐like protease, that regulates nitrogenase activity in soybean nodules. Overexpressing NAR5 delayed nodule senescence, enhancing nitrogenase activity, yield, and low‐nitrogen tolerance. The elite haplotype NAR5HapI‐1 linked to superior nitrogenase activity and greater seed weight has been ...
Chao Ma, Hanyu Zhao, Haojie Feng, Xulun Dong, Lin Chen, Mingliang Yang, Runyi Chen, Chengjun Lei, Chunyan Liu, Qingshan Chen, Dawei Xin, Jinhui Wang   +11 more
wiley   +1 more source

Bioprinted Tumor Microenvironment Models Reveal Immune Evasion and Guide CAR‐NK Therapeutic Strategies

Advanced Science, EarlyView.
This study presents a 3D embedded bioprinting platform that recapitulates key stromal features of the tumor microenvironment using fibroblasts and lung‐derived ECM. The model enables functional assessment of CAR‐NK cells and provides a versatile tool to support the development of next‐generation immunotherapeutic strategies against solid tumors ...
Dahong Kim, Seona Jo, In‐Hwan Jang, Yu‐Jin Kim, Youngmee Jung, Junhyoung Ahn, Hyungjun Lim, Jae Jong Lee, Kangwon Lee, Tae‐Don Kim, Su A Park   +10 more
wiley   +1 more source

Are current microscopic traffic models capable of generating jerk profile consistent with real world observations?

International Journal of Transportation Science and Technology
Microscopic behavior modeling plays a critical role in traffic flow analyais, simulation, and autonomous vehicle algorithm development. Numerous efforts are devoted to the development of it in both longitudinal and lateral dimensions.
Hongsheng Qi
doaj   +1 more source

Cross-Comparison and Calibration of Two Microscopic Traffic Simulation Models for Complex Freeway Corridors with Dedicated Lanes

Journal of Advanced Transportation, 2019
Realistic microscopic traffic simulation is essential for prospective evaluation of the potential impacts of new traffic control strategies. Freeway corridors with interacting bottlenecks and dedicated lanes generate complex traffic flow phenomena and ...
Xingan (David) Kan, Lin Xiao, Hao Liu, Meng Wang, Wouter J. Schakel, Xiao-Yun Lu, Bart van Arem, Steven E. Shladover, Robert A. Ferlis   +8 more
doaj   +1 more source

ANALYSIS OF ALSELMANI SIGNALIZED INTERSECTION IN BENGHAZI - LIBYA [PDF]

, 2013
Intersections play an important role in the road network, where traffic flows in different directions converge. Because of their influence each other, disturbance of pedestrians and bicycle to vehicles, and the lost of green time for beginning and ...

core  

Cuproptosis and Mitophagy Mediated by the THUMPD1/IGF2R‐Dependent Suppression of AKT and Activation of AMPK Signaling Suppress Lung Adenocarcinoma Progression

Advanced Science, EarlyView.
THUMPD1 drives a tumor‐suppressive signaling cascade in lung adenocarcinoma by promoting IGF2R expression. IGF2R associates with PPP2R1A to suppress AKT and activate AMPK, leading to SLC31A1 upregulation and copper accumulation. Elevated copper disrupts mitochondrial metabolism and induces excessive mitophagy, thereby restraining tumor growth and ...
Kai Wu, Bo Qin, Zhuoyu Gu, Weizheng Ding, Xiaoming Chen, Kaishang Zhang, Yujin Qiao, Shuang Yuan, Song Zhao, Xiangnan Li, Peng Zhang   +10 more
wiley   +1 more source

A comparison of microscopic traffic flow simulation systems for an urban area [PDF]

Transport Problems, 2010
The paper compares the results of an application of three selected systems (TRANSIMS, SUMO, and VISSIM) to the microscopic simulation of traffic flow for a fragment of a real urban road network.
Michał MACIEJEWSKI
doaj