Results 41 to 50 of about 14,703,710 (286)

Review of Data Collection Methods for Microscopic Traffic Simulation [PDF]

, 2004
Research into developing more reliable microscopic traffic simulation models is seriously hampered by the availability of suitable microscopic data for calibration and validation purposes.
Wagner, Peter, Hidas, Peter
core  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Autonomous Vehicle Decision and Control through Reinforcement Learning with Traffic Flow Randomization

Machines
Most of the current studies on autonomous vehicle decision-making and control based on reinforcement learning are conducted in simulated environments. The training and testing of these studies are carried out under the condition of rule-based microscopic
Yuan Lin, Antai Xie, Xiao Liu
doaj   +1 more source

Calibration and Validation of Microscopic Traffic Flow Models [PDF]

, 2004
Microscopic simulation models are becoming increasingly important tools in modeling transport systems. There are a large number of available models used in many countries.
Brockfeld, Elmar, Kühne, Reinhart, Wagner, Peter   +2 more
core  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Nautical traffic simulation with multi-agent system [PDF]

, 2013
This paper describes a microscopic nautical traffic simulation model based on multi-agent system. The ship traffic is produced from the behavior of autonomous agents that represent ships.
Coen van Gulijk, Han Ligteringen, Fangliang Xiao, Van Gulijk, Coen, Ale, B.J.M. (author), Ale, B. (author), Ale, B.J.M., Ligteringen, H. (author), Van Gulijk, C. (author), Xiao, F. (author), Ligteringen, Han, Van Gulijk, C., Xiao, F., Ben Ale, Xiao, Fangliang, Ale, Ben, Ligteringen, H.   +16 more
core   +2 more sources

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Multi-Modal Traffic Simulation Calibration and Integration with Real-Time Hardware in Loop Simulator

SUMO Conference Proceedings, 2022
The ongoing research in intelligent transport systems and connected and automated vehicles, enabled by advancements in artificial intelligence, integrating traffic simulations has become an essential part of product/software development for the ...
Vikhyat Kalra, Punit J Tulpule, Jacob A. Isaman   +2 more
doaj   +1 more source

The use of micro-simulation for congested traffic load modelling of medium- and long-span bridges [PDF]

, 2011
This paper presents a new approach to the modelling of congested traffic loading events on long span bridges. Conventional traffic load models are based on weigh-in-motion data of non-congested traffic, or something similar to a Poisson Arrival process ...
O\u27Brien, Eugene J., Walsh, Cathal, O'Brien, Eugene J., Hayrapetova, Alisa   +3 more
core   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source