Results 61 to 70 of about 14,703,710 (286)
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Journal of Advanced Transportation, 2020 Microscopic modeling of mixed traffic (i.e., automaton-driven vehicles and human-driven vehicles) dynamics, particularly car-following, lane-changing, and gap-acceptance, provides the opportunity to gain a more accurate estimation of flow-density ...
Mudasser Seraj +2 more
doaj +1 more source
Microscopic traffic models, accidents, and insurance losses
ASTIN BulletinAbstractThe paper develops a methodology to enable microscopic models of transportation systems to be accessible for a statistical study of traffic accidents. Our approach is intended to permit an understanding not only of historical losses but also of incidents that may occur in altered, potential future systems. Through such a counterfactual analysis,
Sojung Kim, Marcel Kleiber, Stefan Weber
openaire +2 more sources
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
Performance of car following behaviour in microscopic traffic flow models [PDF]
, 2004 Microscopic simulation models are becoming increasingly important tools in modelling transport systems. They are applied in simulation programs for transport planning, traffic forecasting and advanced vehicle control and safety systems (AVCSS).
Brockfeld, Elmar +2 more
core
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Creating Infrastructure for Urban Mobility: Case Study of Skopje
Promet (Zagreb), 2018 In this paper, a methodology for creating and testing new proposed transport infrastructure is presented. It is based on microscopic traffic simulation of current and forecasted traffic demand and in-depth analysis of traffic flow.
Daniela Koltovska Nečoska +2 more
doaj +1 more source
Towards a benchmarking of Microscopic Traffic Flow Models [PDF]
, 2003 Several microscopic traffic models have been tested with a publicly available data set. The task was to predict the travel times between sever observers along a one-lane rural road, given as boundary conditions the flow into this road and the flow out of
Brockfeld, Elmar +3 more
core
Fundamental diagram of traffic flows on urban roads – local versus whole-link approaches [PDF]
, 2009 Fundamental diagrams of traffic flow variables have been quite useful in determining freeway operations quality. However, they are usually not used for that purpose on urban roads.
Elmar Brockfeld +8 more
core +2 more sources
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source