Results 81 to 90 of about 14,703,710 (286)

SUMO in SPACE: Combining SUMO and dSPACE for Advanced Traffic Simulation

SUMO Conference Proceedings
Microscopic traffic simulation tools enable the simulation of various traffic demands and their impacts. By implementing realistic traffic models, they are commonly used to analyze traffic engineering measures.
Christopher Stang, Dennis Roeser
doaj   +1 more source

Comparison of Microscopic Drivers' Probabilistic Lane-changing Models With Real Traffic Microscopic Data [PDF]

, 2011
The difficulties of microscopic-level simulation models to accurately reproduce real traffic phenomena stem not only from the complexity of calibration and validation operations, but also from the structural inadequacies of the sub-models themselves ...
Mohammad Sadat Hoseini, Seyyed, Seyyed Mohammad Sadat Hoseini   +1 more
core   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Using Probe Counts to Provide High-Resolution Detector Data for a Microscopic Traffic Simulation

Vehicles
Microscopic traffic simulations have become increasingly important for research targeting connected vehicles. They are especially appreciated for enabling investigations targeting large areas, which would be practically impossible or too expensive in the
Tobias Veihelmann, Victor Shatov, Maximilian Lübke, Norman Franchi   +3 more
doaj   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

GIS Mapping of Driving Behavior Based on Naturalistic Driving Data

ISPRS International Journal of Geo-Information, 2019
Naturalistic driving can generate huge datasets with great potential for research. However, to analyze the collected data in naturalistic driving trials is quite complex and difficult, especially if we consider that these studies are commonly conducted ...
José Balsa-Barreiro, Pedro M. Valero-Mora, José L. Berné-Valero, Fco-Alberto Varela-García   +3 more
doaj   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

The Effect of Driver Behavior on Energy Consumption Using a Microscopic Traffic Model

IEEE Access
Driver behavior significantly affects vehicle energy consumption and emissions which are critical global concerns. This paper proposes a microscopic traffic model to characterize energy consumption considering the physiological and psychological behavior
Zawar Hussain Khan, Faryal Ali, Khurram Shehzad Khattak, Ahmed B. Altamimi, Mohammad Alsaffar, Wilayat Khan, Thomas Aaron Gulliver   +6 more
doaj   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

microRNA‐7‐5p and α‐Synuclein SAA Predict Parkinson's Disease Phenoconversion

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Corroborate blood neuron‐derived extracellular vesicle (NDEV) alpha‐synuclein (αSyn), the CSF αSyn seed amplification assay (αSyn‐SAA), and blood microRNA‐7‐5p (miR‐7‐5p) as markers for Parkinson's disease (PD) phenoconversion and determine if combining these markers would help select subjects who would be more likely to phenoconvert.
Shayan Zadegan, Praveen Velammal, Kanmani Muthiah, Madhu Jatty, Christopher Adams   +4 more
wiley   +1 more source