Results 61 to 70 of about 5,113,203 (370)

Twin-Photon Confocal Microscopy

, 2010
A recently introduced two-channel confocal microscope with correlated detection promises up to 50% improvement in transverse spatial resolution [Simon, Sergienko, Optics Express {\bf 18}, 9765 (2010)] via the use of photon correlations.
A. V. Sergienko, D. S. Simon, Denk, Denk, Heintzmann, Lukosz, Pittman, Sheppard, Simon, Török, Török, Török, Wilson   +12 more
core   +1 more source

Evaluating performance in three-dimensional fluorescence microscopy [PDF]

, 2007
In biological fluorescence microscopy, image contrast is often degraded by a high background arising from out of focus regions of the specimen. This background can be greatly reduced or eliminated by several modes of thick specimen microscopy, including ...
Chong F.K., Conchello J.A., Patterson G.H., Sandison D.R., Sandison D.R., Shapiro H.M., Tsien R.Y.   +6 more
core   +3 more sources

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

FEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue, Sandrine Picaud, Régine Hepp, Stéphanie Pons, Uwe Maskos, Bertrand Lambolez, Ludovic Tricoire   +6 more
wiley   +1 more source

Methods to evaluate the twin formation energy: comparative studies of the atomic simulations and in-situ TEM tensile tests

Applied Microscopy, 2020
Deformation twinning, one of the major deformation modes in a crystalline material, has typically been analyzed using generalized planar fault energy (GPFE) curves.
Hong-Kyu Kim, Sung-Hoon Kim, Jae-Pyoung Ahn   +2 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Microscopic research on the olfactory organ of the Far Eastern brook lamprey Lethenteron reissneri (Pisces, Petromyzontidae)

Applied Microscopy, 2020
The olfactory anatomy and histology of Lethenteron reissneri were researched using a stereo microscope, a light microscope, and a scanning electron microscope.
Hyun-Tae Kim, Jong-Young Park
doaj   +1 more source

Fractal dimension analysis as an easy computational approach to improve breast cancer histopathological diagnosis

Applied Microscopy, 2021
Histopathology is a well-established standard diagnosis employed for the majority of malignancies, including breast cancer. Nevertheless, despite training and standardization, it is considered operator-dependent and errors are still a concern.
Lucas Glaucio da Silva, Waleska Rayanne Sizinia da Silva Monteiro, Tiago Medeiros de Aguiar Moreira, Maria Aparecida Esteves Rabelo, Emílio Augusto Campos Pereira de Assis, Gustavo Torres de Souza   +5 more
doaj   +1 more source

Light sheet microscopy with acoustic sample confinement [PDF]

, 2019
Contactless sample confinement would enable a whole host of new studies in developmental biology and neuroscience, in particular, when combined with long-term, wide-field optical imaging.
Cochran, Sandy, Cole, Katy L.H., Dholakia, Kishan, Lyons, David A., Nylk, Jonathan, Qiu, Yongqiang, Somorjai, Ildikó M.L., Spalding, Gabriel C., Wijesinghe, Philip, Yang, Zhengyi   +9 more
core   +7 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Scanning acoustic microscopy for material evaluation

Applied Microscopy, 2020
Scanning acoustic microscopy (SAM) or Acoustic Micro Imaging (AMI) is a powerful, non-destructive technique that can detect hidden defects in elastic and biological samples as well as non-transparent hard materials. By monitoring the internal features of
Hyunung Yu
doaj   +1 more source