Results 71 to 80 of about 2,725 (177)

Hybrid Membrane‐Coated Nanoparticles for Precise Targeting and Synergistic Therapy in Alzheimer's Disease

open access: yesAdvanced Science, Volume 11, Issue 24, June 26, 2024.
A novel cell membrane coating is designed by hybridizing the membranes from platelets and chemokine receptor 2 overexpressing cells to cross the blood brain barrier (BBB) and target neuroinflammatory lesions. Rapamycin and 1‐trifluoromethoxyphenyl‐3‐(1‐propionylpiperidin‐4‐yl) urea (TPPU) are loaded into the liposomes to achieve a synergistic therapy ...
Rong‐Rong Lin   +9 more
wiley   +1 more source

Catalytic activities of mammalian epoxide hydrolases with cis and trans fatty acid epoxides relevant to skin barrier function

open access: yesJournal of Lipid Research, 2018
Lipoxygenase (LOX)-catalyzed oxidation of the essential fatty acid, linoleate, represents a vital step in construction of the mammalian epidermal permeability barrier.
Haruto Yamanashi   +6 more
doaj  

Global, regional, and national burden and trends of early‐onset tracheal, bronchus, and lung cancer from 1990 to 2019

open access: yesThoracic Cancer, Volume 15, Issue 8, Page 601-613, March 2024.
Tracheal, bronchus, and lung cancer (TBL) is one of the main cancer health problems worldwide, but data on the burden and trends of EO‐TBL cancer are sparse. Our aim was to provide the latest and the most comprehensive burden estimates of the EO‐TBL cancer from 1990 to 2019.
Jun Ma, Ying‐da Song, Xiao‐ming Bai
wiley   +1 more source

Abstracts

open access: yesMolecular Oncology, Volume 19, Issue S1, Page 1-895, June 2025.
Abstracts submitted to the ‘EACR 2025 Congress: Innovative Cancer Science’, from 16–19 June 2025 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

GST polymorphism as a predictive biomarker for modulating the susceptibility to chronic obstructive pulmonary disease: A North Indian study

open access: yesExperimental Physiology, Volume 109, Issue 2, Page 302-311, 1 February 2024.
Abstract Chronic obstructive pulmonary disease (COPD) is commonly characterized by shortness of breath, coughing or expectoration. Smoking is the leading cause of COPD development, but only a small percentage of smokers develop symptoms, implying a genetic component.
Harsh Yadav   +9 more
wiley   +1 more source

Chiral lipidomics of monoepoxy and monohydroxy metabolites derived from long-chain polyunsaturated fatty acids[S]

open access: yesJournal of Lipid Research, 2019
A chiral lipidomics approach was established for comprehensive profiling of regio- and stereoisomeric monoepoxy and monohydroxy metabolites of long-chain PUFAs as generated enzymatically by cytochromes P450 (CYPs), lipoxygenases (LOXs), and ...
Maximilian Blum   +4 more
doaj  

Relative Importance of Soluble and Microsomal Epoxide Hydrolases for the Hydrolysis of Epoxy-Fatty Acids in Human Tissues [PDF]

open access: gold, 2021
Christophe Morisseau   +5 more
openalex   +1 more source

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