Results 101 to 110 of about 50,037 (190)

Insights into the Metabolism, Disposition, and Quantitative Profile of mGlu5 NAM AE90015 with Metabolite Identification and a Novel Integration Method. [PDF]

Molecules
Zou ZZ, Han MJ, Chang Y, Li G.
europepmc   +1 more source

Assessment of SREBP Activation Using a Microsomal Vesicle Budding Assay. [PDF]

Bio Protoc
Xia M, Edwards T, Rong S.
europepmc   +1 more source

Heterocyclic phytometabolites formononetin and arbutin prevent in vitro oxidative and alkylation-induced mutagenicity. [PDF]

Toxicol Rep
Santos LVS, Galvão BVD, Souza L, Fernandes ADS, Araujo-Lima CF, Felzenszwalb I.   +5 more
europepmc   +1 more source

Characterization of Neonicotinoid Metabolites by Cytochrome P450-Mediated Metabolism in Poultry. [PDF]

Toxics
Dam-On A, Nimako C, Kulprasertsri S, Ikenaka Y, Yohannes YB, Nakayama SMM, Ishizuka M, Poapolathep S, Poapolathep A, Khidkhan K.   +9 more
europepmc   +1 more source

Enrichment of ER tubule-derived microsomes by differential centrifugation and immunoprecipitation. [PDF]

Biophys Rep
Liu Y, Hu J, Yan B.
europepmc   +1 more source

Miniaturized click chemistry and direct screening facilitate the discovery of triazole piperazine SARS-CoV-2 M^pro inhibitors with improved metabolic stability. [PDF]

RSC Med Chem
Gao S, Song L, Ye B, Yang M, Li J, Gu M, Tollefson AE, Toth K, Zhan P, Liu X.   +9 more
europepmc   +1 more source

StaufenC facilitates utilization of the ERAD pathway to transport dsRNA through the endoplasmic reticulum to the cytosol. [PDF]

Proc Natl Acad Sci U S A
Koo J, Palli SR.
europepmc   +1 more source

Structure-Based Optimization of Selective and Brain Penetrant CK1δ Inhibitors for the Treatment of Circadian Disruptions. [PDF]

ACS Med Chem Lett
McCarver S, Hanna L, Samant A, Thompson AA, Seierstad M, Saha A, Wu D, Lord B, Sutton SW, Shah V, Milligan CM, Wennerholm M, Shelton J, Lebold TP, Shireman BT.   +14 more
europepmc   +1 more source

Galectin-8N-Selective 4-Halophenylphthalazinone-Galactals Double π-Stack in a Unique Pocket. [PDF]

ACS Med Chem Lett
van Klaveren S, Hassan M, Håkansson M, Johnsson RE, Larsson J, Jakopin Ž, Anderluh M, Leffler H, Tomašič T, Nilsson UJ.   +9 more
europepmc   +1 more source

Hybrid fragment-SMILES tokenization for ADMET prediction in drug discovery. [PDF]

BMC Bioinformatics
Aksamit N, Tchagang A, Li Y, Ombuki-Berman B.   +3 more
europepmc   +1 more source