Results 111 to 120 of about 74,782 (341)

Construction of a synthetic messenger RNA encoding a membrane protein. [PDF]

open access: yes, 1983
We have synthesized microgram quantities of a functional eucaryotic mRNA by in vitro transcription. For this purpose, we constructed a plasmid in which the Escherichia coli lactose promoter was 5' to the vesicular stomatitis virus (VSV) G protein gene ...
Chappell, TG, Rubenstein, JL
core  

Isoflavone glycosides: Synthesis and evaluation as α-glucosidase inhibitors [PDF]

open access: yes, 2008
On the basis of the structure of 4′,7,8-trihydroxyisoflavone 7-O-α-D-arabinofuranoside (namely A-76202, 1), a Rhodococcus metabolite showing potent inhibitory activities against the α-glucosidases of rat liver microsome (IC 50 = 0.46 ng/mL), 26 analogs ...
Asano   +36 more
core   +1 more source

Electrokinetic Manipulations Combined With Direct and Ambient Ionization Mass Spectrometry

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Mass spectrometry (MS) is a powerful analytical technique that typically involves sample preparation and online analytical separation before MS detection. Traditional methods often face bottlenecks in sample preparation and analytical separation, despite the rapid detection capabilities of MS.
Nicholas E. Manicke   +2 more
wiley   +1 more source

Amino acid intake & body protein synthesis [PDF]

open access: yes, 1969
Cover title."Lecture presented Feb. 7, 1967, at the University of Missouri-Columbia"--P. 4.Includes bibliographical references (pages 23-24)
Munro, Hamish N. (Hamish Nisbet)
core  

Astatine‐211—Towards In Vivo Stable Astatine‐211 Labeled Radiopharmaceuticals and Their (Pre)Clinical Applications

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Targeted radioligand therapy has emerged as a promising treatment option for eradicating advanced cancer forms. α‐Emitters are considered particularly promising as they can obliterate (micro)‐metastases. The α‐emitter astatine‐211 (211At) has experienced increased interest due to its favorable decay properties.
Marius Müller   +5 more
wiley   +1 more source

Metabolism of Epoxidised Withanolides by a Generalist and a Specialist Insect Species

open access: yesChemistryOpen, EarlyView.
Larvae of Heliothis (Chloridea) virescence and subflexa have the ability to convert the epoxidized terpenoid 4β‐hydroxywithanolide E (4BHWE) to withanolide S. The conversion is found by feeding the larvae an artificial diet supplemented with 13C‐labeled 4BHWE.
Marie Pauline Sell   +4 more
wiley   +1 more source

A comparison of the prevalence of anti-Liver/Kidney Microsome antibody type-1(LKM-1) in individuals with chronic hepatitis C and those with autoimmune hepatitis

open access: yesمجلة كلية الطب, 2007
Background: Autoantibodies are frequently found in patients with chronic hepatitis C, which suggests that HCV elicit an immune response in the host. ).
Eman Sh. AL- Obeidy   +2 more
doaj  

Development of a physiologically‐based pharmacokinetic model for Ritonavir characterizing exposure and drug interaction potential at both acute and steady‐state conditions

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 523-539, March 2025.
Abstract Ritonavir (RTV) is a potent CYP3A inhibitor that is widely used as a pharmacokinetic (PK) enhancer to increase exposure to select protease inhibitors. However, as a strong and complex perpetrator of CYP3A interactions, RTV can also enhance the exposure of other co‐administered CYP3A substrates, potentially causing toxicity.
Lien Thi Ngo   +5 more
wiley   +1 more source

ER Microsome Preparation and Subsequent IAA Quantification in Maize Coleoptile and Primary Root Tissue

open access: yesBio-Protocol, 2016
Auxin is a major growth hormone in plants and the first plant hormone to be discovered and studied (Darwin and Darwin, 1880). The auxin molecule in plants was first identified as indole-3-acetic acid (IAA) by Kögl et al. (1934).
Verena Kriechbaumer
doaj   +1 more source

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