Results 121 to 130 of about 50,037 (190)

Serum and tear autoantibodies from NOD and NOR mice as potential diagnostic indicators of local and systemic inflammation in Sjögren's disease. [PDF]

Front Immunol
Singh Kakan S, Abdelhamid S, Ju Y, MacKay JA, Edman MC, Raman I, Zhu C, Raj P, Hamm-Alvarez SF.   +8 more
europepmc   +1 more source

Metabolic and Pharmacokinetic Profiling Studies of N, N-Dimethylaniline-Heliamine in Rats by UHPLC-Q-Orbitrap MS/MS. [PDF]

Molecules
Xi R, Abdulla R, Sherzod J, Ivanovna VV, Habasi M, Liu Y.   +5 more
europepmc   +1 more source

Multifaceted delineation of atrophic thyroiditis among pediatric population: An extensive literature survey. [PDF]

Clin Pediatr Endocrinol
Motegi S, Adachi M, Nagahara K, Ishida T, Ochi A, Mizuno K.   +5 more
europepmc   +1 more source

Inhibition of Tacrolimus Metabolism by Cannabidiol and Its Metabolites In Vitro. [PDF]

Clin Transl Sci
So GC, Lu JBL, Cheng YH, Gisch DL, Koyama S, Melo Ferreira R, Beamon TR, Desta Z, Eadon MT.   +8 more
europepmc   +1 more source

The in vivo metabolic pathway of Deg-AZM and in vitro investigations into the contribution of drug metabolizing enzymes and drug transporters in the drug interactions of Deg-AZM, a clinical-stage new transgelin agonist. [PDF]

Front Pharmacol
Gu X, Li X, Tian W, Zheng C, Cai Y, Xu X, Zhao C, Liu H, Sun Y, Luo Z, Zhu S, Zhou H, Ai X, Yang C.   +13 more
europepmc   +1 more source

Tracking and recording of intracellular oxygen concentration changes in cell organelles: preparation and function of azide-modified fluorescent probes. [PDF]

RSC Adv
Makanai H, Kanda M, Harada S, Nishihara T, Tanabe K.   +4 more
europepmc   +1 more source

Evaluating in vivo data for drug metabolism and transport: lessons from Kirchhoff's Laws. [PDF]

Front Pharmacol
Benet LZ, Sodhi JK.
europepmc   +1 more source

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The preparation of microsomes

Naunyn-Schmiedebergs Archiv f�r Experimentelle Pathologie und Pharmakologie, 1965
Various methods of disrupting liver cells and preparing microsomes were studied. The quality and yield of the microsomes in the preparations was judged by the NADPH-dependent N- and p-hydroxylation of N-ethylaniline, protein content, and cyanide-sensitive respiration.
Hermann G. Kampffmeyer, Rosemarie von Jagow, Manfred Kinese   +2 more
openaire   +3 more sources

Microsomal metabolism of fluoroanilines

Xenobiotica, 1989
1. The microsomal, cytochrome P-450-dependent metabolism of fluoroanilines was studied using 19F-n.m.r. and also by a chemical assay for the hydroxy derivatives. 2. 2-Fluoro- and 3-fluoroaniline were preferentially hydroxylated at the para-position. 3. 4-Fluoroaniline was both p- and o-hydroxylated to a significant extent. 4.
Rietjens, I.M.C.M., Vervoort, J.
openaire   +4 more sources

Miniaturization of the microsuspension Salmonella/microsome assay in agar microplates

Environmental and Molecular Mutagenesis, 2018
The Salmonella/microsome assay (Ames test) is the most widely used mutagenicity test for the evaluation of pure chemicals and environmental samples. There are several versions of protocols available in the literature, including those that reduce the ...
J. R. R. M. Zwarg, D. A. Morales, B. S. Maselli, W. Brack, G. Umbuzeiro   +4 more
semanticscholar   +1 more source