Results 141 to 150 of about 50,037 (190)

Comparison of the Salmonella/microsome microsuspension assay with the new microplate fluctuation protocol for testing the mutagenicity of environmental samples

Environmental and Molecular Mutagenesis, 2009
The objective of this study was to compare the responses of the Salmonella/microsome microsuspension assay with the new microplate fluctuation protocol (MPF) for the evaluation of the mutagenic activity of environmental samples. Organic extracts of total
G. Umbuzeiro, C. M. Rech, S. Correia, A. Bergamasco, Giselli H. L. Cardenette, S. Flückiger-Isler, M. Kamber   +6 more
semanticscholar   +1 more source

Lipid Peroxidation of Rat‐Liver Microsomes [PDF]

European Journal of Biochemistry, 1973
Rat liver microsomes were peroxidized in vitro and chemical, physical and morphological changes in the membrane were related to the effects on certain membrane‐bound microsomal enzymes.With increasing peroxidation, microsomal phospholipids revealed decreasing concentrations of 20:4 and 22:6 fatty acids.
Anders Bergstrand, Johan Högberg, Sten V. Jakobsson   +2 more
openaire   +2 more sources

Isolation of high molecular weight components and contribution to the protective activity of coffee against lipid peroxidation in a rat liver microsome system.

Journal of Agricultural and Food Chemistry, 2008
One of the most extensively studied and best-established properties of coffee is its antioxidant activity. We have shown that coffee brew has the ability to inhibit lipid peroxidation completely in a rat liver microsome biological system.
M. Daglia, A. Papetti, Camilla Aceti, Barbara Sordelli, C. Gregotti, G. Gazzani   +5 more
semanticscholar   +1 more source

Heterocyclic compounds: Toxic effects using algae, daphnids, and the Salmonella/microsome test taking methodical quantitative aspects into account

Environmental Toxicology and Chemistry, 2008
Heterocyclic aromatic hydrocarbons containing nitrogen, sulfur, or oxygen (NSO‐HET), have been detected in air, soil, sewage sludge, marine environments, and freshwater sediments.
A. Eisentraeger, C. Brinkmann, H. Hollert, A. Sagner, A. Tiehm, J. Neuwoehner   +5 more
semanticscholar   +1 more source

Mutagenicity of medicinal plant extracts in Salmonella/microsome assay.

Phytotherapy Research, 1999
Aqueous extracts of medicinal plants used in south Brazilian folk medicine (Myrciaria tenella, Smilax campestris, Tripodanthus acutifolius and Cassia corymbosa) were screened for the presence of mutagenic activity in the Salmonella/microsome assay. Signs
Isabel C F R Ferreira, V. M. Vargas
semanticscholar   +2 more sources

A preliminary characterization of the mutagenicity of atmospheric particulate matter collected during sugar cane harvesting using the Salmonella/microsome microsuspension assay

Environmental and Molecular Mutagenesis, 2008
During sugar cane harvesting season, which occurs from May to November of each year, the crops are burnt, cut, and transported to the mills. There are reports showing that mutagenic activity and PAH content increase during harvesting season in some areas
G. de Aragão Umbuzeiro, A. Franco, D. Magalhães, F. J. V. de Castro, Fábio Kummrow, C. M. Rech, Lilian Rothschild Franco de Carvalho, Pérola de Castro Vasconcellos   +7 more
semanticscholar   +1 more source

Human liver microsome-mediated metabolism of brominated diphenyl ethers 47, 99, and 153 and identification of their major metabolites.

Chemical Research in Toxicology, 2009
While the metabolism and excretion of polybrominated diphenyl ethers (PBDEs) have been reported in rodents, PBDE metabolism in humans has only recently been investigated. In this present study, individual human liver microsomes were incubated for 120 min
Sara J. Lupton, B. McGarrigle, J. Olson, T. D. Wood, D. Aga   +4 more
semanticscholar   +1 more source

Identification and analysis of cytochrome P450IID6 antigenic sites recognized by anti‐liver‐kidney microsome type‐1 antibodies (LKM1)

European Journal of Immunology, 1993
Anti‐liver‐kidney microsome type‐1 antibodies (LKM1), present in sera from a group of patients with autoimmune hepatitis, are directed against P450IID6.
A. Yamamoto, D. Cresteil, Odile Boniface, F. Clerc, F. Alvarez   +4 more
semanticscholar   +1 more source

Studies on the genotoxic properties of essential oils with Bacillus subtilis rec-assay and Salmonella/microsome reversion assay.

Planta Medica, 1991
Genotoxic properties of essential oils from Anthemis nobilis L., Artemisia dracunculus L., Salvia officinalis L., Salvia sclarea L., Satureja hortensis L., Satureja montana L., Thymus capitatus L., Thymus citriodorus Schreb., Thymus vulgaris L., Citrus ...
F. Zani, G. Massimo, Stefania Benvenuti, Alberto Bianchi, A. Albasini, M. Melegari, G. Vampa, A. Bellotti, P. Mazza   +8 more
semanticscholar   +1 more source

[30] Microsomal lipid peroxidation

1978
Publisher Summary This chapter discusses microsomal lipid peroxidation. Lipid peroxidation is a complex process known to occur in both plants and animals. It involves the formation and propagation of lipid radicals, the uptake of oxygen, a rearrangement of the double bonds in unsaturated lipids, and the eventual destruction of membrane lipids ...
Steven D. Aust, John A. Buege
openaire   +3 more sources