Results 151 to 160 of about 24,113 (256)

Evaluation of in vitro drug-drug interactions of ivermectin and antimalarial compounds. [PDF]

Malar J
Tipthara P, Kullasakboonsri R, Kobylinski KC, Tarning J.   +3 more
europepmc   +1 more source

Inhibitory effect of the combination of notoginseng total saponins and safflower total flavonoids on UDP-glucuronosyltransferases 1A1, 1A4, and 2B7 in human liver microsomes

, 2019
Yan Li
openalex   +1 more source

Autoimmune Hepatitis: Histopathological Diversity and Its Clinical Implications

Hepatology Research, Volume 56, Issue 2, Page 139-147, February 2026.
ABSTRACT Autoimmune hepatitis (AIH) is a chronic inflammatory liver disease characterized by diverse clinical and histological manifestations. Accurate histopathological evaluation plays a critical role in determining disease activity, guiding treatment strategies, and predicting prognosis.
Mina Komuta, Kenichi Harada
wiley   +1 more source

Biosynthesis and Identification of Clenbuterol Metabolites in Urine and In Vitro Microsome Incubation Samples Using UHPLC-Q-Exactive Orbitrap Mass Spectrometry: A Comparison Between Human and Bovine Metabolism. [PDF]

Drug Test Anal
Gómez-Tagle A, Bressan C, Ventura R, Álvarez-Sanchez A, Cardenas-Yong E, Velasco-Bejarano B.   +5 more
europepmc   +1 more source

Evaluation of Pathogenic Variants Associated With Monogenic Disorders of Dyslipidemia in Patients With Well Characterised MASLD

Liver International, Volume 46, Issue 2, February 2026.
ABSTRACT Background and Aims Dyslipidemia is common in patients with MASLD, but the frequency and significance of inherited disorders of dyslipidemia are unclear. We investigated the prevalence and significance of pathogenic variants associated with selected monogenic disorders of dyslipidemia in 3358 patients with well‐characterised MASLD. Approach We
Tae‐Hwi Schwantes‐An, Marco A. Abreu, Brent A. Neuschwander‐Tetri, Jian Wang, Xiuqing Guo, Jingyi Tan, Robert A. Hegele, Nicholas O. Davidson, Luca Lotta, Niek Verweij, Katherine P. Yates, Jerome I. Rotter, Naga Chalasani   +12 more
wiley   +1 more source

Editorial: Non-invasive methods in drug metabolism and transport: insights from biological samples to oral administration. [PDF]

Front Pharmacol
Wróblewski K, Zheng Y, Yue X.
europepmc   +1 more source

Effect of Efavirenz on UDP-Glucuronosyltransferase 1A1, 1A4, 1A6, and 1A9 Activities in Human Liver Microsomes [PDF]

, 2012
Hye Young Ji, Hyeri Lee, Sae Rom Lim, Jeong‐Han Kim, Hye Suk Lee   +4 more
openalex   +1 more source

Sex‐dependent role of 20‐HETE synthesis in outcome from ischemic stroke in rats

Physiological Reports, Volume 14, Issue 3, February 2026.
Abstract The lipid mediator 20‐HETE is produced by ω‐hydroxylation of arachidonic acid mediated by cytochrome P450 (CYP) enzymes including CYP4A, which has four distinct isoforms in rodents. Several laboratories demonstrated that 20‐HETE synthesis inhibition reduces infarct volume following middle cerebral artery occlusion (MCAO) in male animals. Here,
Rongrong Zhang, Yanrong Shi, Suyi Cao, Raymond C. Koehler, Zeng‐Jin Yang   +4 more
wiley   +1 more source

A perspective review on factors that influence mutagenicity in medicinal plants and their health implications. [PDF]

Toxicol Sci
Fasiku V, Kyagaba D, Hlalele A, Adegoke A, Erukainure OL, Sekhoacha M.   +5 more
europepmc   +1 more source

Oxygen Radical Generation by Isolated Microsomes from Soybean Seedlings [PDF]

, 1992
Marcela Simontacchi, Susana Puntarulo
openalex   +1 more source