Results 61 to 70 of about 50,037 (190)

Effects of psoralen on the pharmacokinetics of anastrozole in rats

open access: yesPharmaceutical Biology, 2018
Context: Psoralen and anastrozole are always used together for breast cancer patients in Chinese clinics. Objective: This study investigates the effects of psoralen on the pharmacokinetics of anastrozole in rats and its potential mechanism. Materials and
Yuzhu Zhang   +4 more
doaj   +1 more source

Total Synthesis and Metabolic Stability of Hispidulin and Its d-Labelled Derivative

open access: yesMolecules, 2017
Hispidulin is a naturally occurring flavone known to have various Central nervous system (CNS) activities. Proposed synthetic approaches to synthesizing hispidulin have proven unsatisfactory due to their low feasibility and poor overall yields.
Liang-Chieh Chen   +4 more
doaj   +1 more source

Microsomal epoxide hydrolase polymorphisms

open access: yesMolecular Medicine Reports, 2010
Microsomal epoxide hydrolase plays a dual role in the activation and detoxification of carcinogenic compounds. Two polymorphic sites have been described in exons 3 and 4 of the microsomal epoxide hydrolase gene that change tyrosine residue 113 to histidine (Tyr113His) and histidine 139 to arginine (His139Arg), respectively.
Pinarbasi, Hatice   +2 more
openaire   +6 more sources

Anti-liver-kidney microsome antibody recognizes a 50,000 molecular weight protein of the endoplasmic reticulum

open access: yesJournal of Experimental Medicine, 1985
Children with autoimmune chronic active hepatitis may have high titers of antibodies detected by immunofluorescence staining of hepatocytes and tubular cells in rat liver and kidney sections, respectively.
F. Alvarez   +3 more
semanticscholar   +1 more source

Microsomes are the in vitro ER

open access: yesThe Journal of Cell Biology, 2005
![Graphic][1] Microsomes (here) and ER look similar, and both have ribosomes (see dots near “ob2”). PALADEThe abundance of electron microscope (EM) images in the 1940s and 1950s brought a new problem: nomenclature. What to call all those black smudges?
openaire   +3 more sources

Anti-liver-kidney microsome antibody-positive autoimmune hepatitis presenting as fulminant liver failure.

open access: yesJournal of Pediatric Gastroenterology and Nutrition - JPGN, 1990
A 17-month-old girl presented with acute hepatitis, which took a fulminant course leading to death 2 months after onset. No known cause of fulminant liver failure could be identified.
G. Porta, L. Gayotto, F. Alvarez
semanticscholar   +1 more source

ER Microsome Preparation and Subsequent IAA Quantification in Maize Coleoptile and Primary Root Tissue

open access: yesBio-Protocol, 2016
Auxin is a major growth hormone in plants and the first plant hormone to be discovered and studied (Darwin and Darwin, 1880). The auxin molecule in plants was first identified as indole-3-acetic acid (IAA) by Kögl et al. (1934).
Verena Kriechbaumer
doaj   +1 more source

A comparison of the prevalence of anti-Liver/Kidney Microsome antibody type-1(LKM-1) in individuals with chronic hepatitis C and those with autoimmune hepatitis

open access: yesمجلة كلية الطب, 2007
Background: Autoantibodies are frequently found in patients with chronic hepatitis C, which suggests that HCV elicit an immune response in the host. ).
Eman Sh. AL- Obeidy   +2 more
doaj  

Analyzing the topology of N-linked glycans by PNGase F accessibility assay

open access: yesSTAR Protocols, 2023
Summary: While N-glycans are synthesized in the lumens, some of them reach the cytosolic side of membranes through retro-translocation independent of endoplasmic-reticulum-associated degradation.
Jingcheng Wang, Jin Ye
doaj  

Antimutagenic activity of cashew apple (Anacardium occidentale Sapindales, Anacardiaceae) fresh juice and processed juice (cajuína) against methyl methanesulfonate, 4-nitroquinoline N-oxide and benzo[a]pyrene

open access: yesGenetics and Molecular Biology, 2008
Cashew apple juice (CAJ), produced from the native Brazilian cashew tree (Anacardium occidentale), and has been reported to have antibacterial, antifungal, antitumor, antioxidant and antimutagenic properties.
Ana Amelia Melo-Cavalcante   +3 more
doaj   +1 more source

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