Results 211 to 220 of about 56,066 (278)

Interaction of Cytochrome P450 3A4 with Fatty Acid Binding Protein 1 and Relevance to Drug Metabolism. [PDF]

J Med Chem
McCarty KD, Proffett DLD, Guengerich FP.
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Effects of Newer Veterinary Macrolide Antimicrobials on the CYP3A-Dependent Metabolism in Cattle Liver Microsomes: Potential Metabolic Drug-Drug Interaction with Monensin. [PDF]

Animals (Basel)
Ichinose P, Munafó JP, Miró MV, Valente M, Moreno-Torrejón L, Larsen K, Lanusse C, Lifschitz A, Virkel G.   +8 more
europepmc   +1 more source

RUNX2 inhibitor CADD522 improves bone microarchitecture and lipid metabolism in post-menopausal bone loss. [PDF]

NPJ Drug Discov
Ersek A, Kim MS, Suelzu C, Piec I, Matsangos A, Nurmemmedov E, Bull EC, Bartlett T, Dunn R, Dick JR, Lapidus R, Copeman DM, Tang JCY, Crichton PG, Pontifex MG, Fraser WD, Horwood NJ, Passaniti A, Green D.   +18 more
europepmc   +1 more source

Development of an LC-MS/MS method to quantitatively analyze escitalopram and its metabolites with application in liver and placenta microsome metabolism. [PDF]

Front Pharmacol
Shen Y, Yao B, Guo Y, Yang Y, Liang C, Huang J, Zhang Y, Wang X.   +7 more
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Reductive dominance and limited cytochrome P450 activity in neonicotinoid metabolism by elephant liver microsomes. [PDF]

J Vet Med Sci
Watanabe K, Khidkhan K, Saengtienchai A, Somgrid C, Towiboon P, Angkawanish T, Langkaphin W, Namwongprom K, Kittisirik N, Yohannes YB, Ikenaka Y, Nakayama SM, Ishizuka M.   +12 more
europepmc   +1 more source

Comparative analysis of sex-based, vendor-based, and species differences in cytochrome P450 metabolism. [PDF]

Sci Rep
Kinatukara N, Xu X, Shah P.
europepmc   +1 more source

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The preparation of microsomes

Naunyn-Schmiedebergs Archiv f�r Experimentelle Pathologie und Pharmakologie, 1965
Various methods of disrupting liver cells and preparing microsomes were studied. The quality and yield of the microsomes in the preparations was judged by the NADPH-dependent N- and p-hydroxylation of N-ethylaniline, protein content, and cyanide-sensitive respiration.
R, von Jagow, H, Kampffmeyer, M, Kiese
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Microsomal Proteomics

2009
Proteomic profiling of subcellular compartments has many advantages over traditional proteomic approaches using whole cell lysates as it allows for detailed proteome analysis of a specific organelle and corresponding functional characteristics. The microsome is a critical, membranous compartment involved in the synthesis, sorting, and secretion of ...
Diana M, Wong, Khosrow, Adeli
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Fusion of microsomal vesicles

Experientia, 1978
Studies which indicate the fusion of rat liver microsomal vesicles show that the rate of fusion of microsomal vesicles, as revealed by electron microscopic examinations, is dependent on the fusion temperature and the amount of detergent present in the microsomal suspension.
H U, Schulze, L, Pop
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