Results 201 to 210 of about 96,126 (327)

In Vitro Metabolism and Analytical Characterization of SLU‐PP‐332 and SLU‐PP‐915: Novel Pan‐ERR Agonists With Doping Potential

Rapid Communications in Mass Spectrometry, Volume 40, Issue 8, 30 April 2026.
ABSTRACT Rationale Estrogen‐related receptor (ERR) agonists such as the drug candidates SLU‐PP‐332 and SLU‐PP‐915 are currently being investigated as exercise mimetics, given their ability to trigger human physiological processes similar to those initiated by actual physical activity.
Tristan Möller, Oliver Krug, Mario Thevis   +2 more
wiley   +1 more source

Investigating the potential role of metabolic resistance genes in conferring cross-resistance to pyrethroids and polycyclic aromatic hydrocarbon pollutants in the major malaria vector Anopheles coluzzii. [PDF]

BMC Genomics
Muhammad A, Ibrahim SS, Ismail HM, Irving H, Paine MJI, Wondji CS.   +5 more
europepmc   +1 more source

Identification of di-2-ethylhexyl terephthalate (DEHTP) metabolites using human liver microsomes for biomonitoring applications

, 2015
Manori J. Silva, Ella Samandar, Antonia M. Calafat, Xiaoyun Ye   +3 more
openalex   +2 more sources

Prenylcysteine Oxidase 1 Deficiency Protects the Cardiac Muscle Cell Line HL‐1 Against Ischaemic/Hypoxic Stress

The FASEB Journal, Volume 40, Issue 8, 30 April 2026.
Ischaemic/hypoxic stress leads to heart remodeling and dysfunction. PCYOX1 promotes cardiomyocyte survival during injury, reducing the generation of reactive oxygen species. PCYOX1 deficiency regulates key proteins to preserve cardiomyocyte structure and function such as creatine kinase.
Cristina Banfi, Lisa Brocca, Alice Bascucci, Giulia Giusy Papaianni, Alice Mallia, Sonia Eligini   +5 more
wiley   +1 more source

In vitro 14 C-glycine incorporation into protein of denervated rat muscle, effect of nandrolonedecanoate [PDF]

, 1967
Krause, P., Scriba, Peter Christian
core   +1 more source

In vitro thyroperoxidase inhibition assessment by LC-ICP-MS-based L-tyrosine iodination assay: comparison with Amplex Ultrared assay and its modifications. [PDF]

Arch Toxicol
Liu R, Novák J, Kuta J, Smutná M, Hilscherová K.   +4 more
europepmc   +1 more source

Fair and Square: Design, Synthesis and Biological Evaluations of Squaric Acid Derivatives as Novel HDAC8 Inhibitors

ChemMedChem, Volume 21, Issue 8, 28 April 2026.
Histone deacetylase 8 (HDAC8) is a clinically validated target in neuroblastoma, where isoform selective inhibition offers a strategy to suppress tumour growth while limiting off‐target toxicity. Hydroxamic acids remain the dominant zinc‐binding group (ZBG) in HDAC inhibitors but are also associated with metabolic instability, suboptimal ...
Nathan Long, Franz‐Josef Meyer‐Almes, Aleksandra Kopranovic, Stephen P. Wren   +3 more
wiley   +1 more source

Characterization of the Formation of the Acyl Glucuronide Metabolite of 7-Carboxy-Cannabidiol in Human Liver, Kidney, and Intestinal Microsomes and <i>in Vivo</i> in Mice. [PDF]

ACS Med Chem Lett
Simon KT, Hailemariam SE, Friedman E, Wen YW, Freaney M, Barker-Haliski M, Isoherranen N.   +6 more
europepmc   +1 more source

A Microsomal Nucleoside Diphosphatase

Journal of Biological Chemistry, 1963
A B, NOVIKOFF, M, HEUS
openaire   +2 more sources

Ferulic acid 5‐hydroxylase: a new cytochrome P‐450‐dependent enzyme from higher plant microsomes involved in lignin synthesis [PDF]

, 1984
Claude Grand
openalex   +1 more source