Results 201 to 210 of about 56,066 (278)

Discovery of a CI-994 derivative as a dual modulator of class I histone deacetylases and Wnt/β-catenin signaling for Alzheimer's disease therapy. [PDF]

Neurotherapeutics
Lu W, Caulfield TR, Lee E, Jeevaratnam S, Wang N, Bu G, Kanekiyo T, Li Y.   +7 more
europepmc   +1 more source

Fangchinoline (2021-2026): A Multitarget Bisbenzylisoquinoline Alkaloid With Emerging Anti-Infective Potential. [PDF]

J Trop Med
Sirwi A, Mohamed HM, Mohamed GA, Eid BG, Abdallah HM, Ibrahim SRM.   +5 more
europepmc   +1 more source

Overlooked aspects of scaling enzyme activity through abundance across tissues and individuals: Insights from k_cat measurements in matched liver and intestinal samples. [PDF]

Drug Metab Dispos
Al-Majdoub ZM, Barber J, Rostami-Hodjegan A, Galetin A, Scotcher D.   +4 more
europepmc   +1 more source

The Effect of Artemisinin on the Pharmacokinetics of Cyclophosphamide and Its Metabolite in Mice and Its Potential Mechanisms. [PDF]

Biomed Chromatogr
Wang H, Zhang W, Hu H, Wang S, Xie Y.
europepmc   +1 more source

Integrated genomic, transcriptomic, and microsomal metabolic profiling of cytochrome P450s in squirrels. [PDF]

J Vet Med Sci
Goto M, Watanabe K, Yohannes YB, Hasegawa N, Morita A, Banda N, Kakisaka K, Ito M, Ikenaka Y, Nakayama SM, Ishizuka M.   +10 more
europepmc   +1 more source

Downregulation of hepatic CYP3A isoforms by bardoxolone methyl in rats and its impact on in vivo metabolic capacity reflecting pharmacokinetics. [PDF]

Sci Rep
Hori Y, Fukuno S, Shirane H, Watanabe R, Murata K, Takenaka M, Konishi H, Nagai K.   +7 more
europepmc   +1 more source

Development of a Hypoxia-Triggered Supramolecular Nanoplatform for Synergistic Hypoxia Alleviation and Amplified Photodynamic Cancer Therapy. [PDF]

Molecules
Luo N, Wu Y, Zheng J, Zhang C, Qian X, Ji C, Jiang A, Ling Y, Liu X.   +8 more
europepmc   +1 more source

The Role of Cytochrome P450 Holoenzyme Metabolism in the Origin of Neuropathologies. [PDF]

Int J Mol Sci
Štambuk S.
europepmc   +1 more source

ENaC processing in rat kidney: effects of salt loading and ADH. [PDF]

Am J Physiol Renal Physiol
Frindt G, Rohan T, Schreiner R, Palmer LG.   +3 more
europepmc   +1 more source

Dietary allicin supplementation inhibits hepatic CYP3A37 in chickens: Evidence from in vitro and in vivo models. [PDF]

Poult Sci
Li Y, Yuan H, Wang J, Yin S, Qiu X, Yang H.   +5 more
europepmc   +1 more source