Results 191 to 200 of about 56,066 (278)

Characterization of Atrasentan Metabolic Pathway in Human Liver Microsomes Using Feature-Based Molecular Networking. [PDF]

Pharmaceutics
Seo HJ, Liang Z, Kim EH, Liu KH.
europepmc   +1 more source

Investigating the Impact of Calcium Channel Blockers on the Pharmacokinetics of Lapatinib: Possible Role of Cytochrome P450 Enzymes and P-glycoprotein Efflux Transporters. [PDF]

Eur J Drug Metab Pharmacokinet
Desai MP, Patil PH, Rajpurohit AUS, Anand VSK, Channabasavaiah JP.   +4 more
europepmc   +1 more source

<i>In Vitro</i> characterization of narciclasine: solubility, metabolic stability, and P-glycoprotein substrate status. [PDF]

Front Pharmacol
Akkireddy R, Yang IH, Lenkalapelly S, Kshirsagar GJ, May HA, Kang MH.   +5 more
europepmc   +1 more source

An Ultra-Fast UPLC-MS/MS Method for Quantifying Ivosidenib: Application to Assessment of Metabolic Stability in Human Liver Microsomes. [PDF]

Arch Pharm (Weinheim)
Attwa MW, Abdelhameed AS, AlRabiah H, Kadi AA.   +3 more
europepmc   +1 more source

Adenosine 5'-Carboxamide-Based Inhibitors of METTL1. [PDF]

ACS Med Chem Lett
Bobileva O, Nai F, Niedrite S, Mayordomo Soler L, Leite I, Caflisch A.   +5 more
europepmc   +1 more source

Cylindrospermopsin toxicokinetics: in silico ADMET modeling, rat and human liver microsome metabolism, and UHPLC-MS/MS metabolite characterization. [PDF]

Arch Toxicol
Cascajosa-Lira A, Guzmán-Guillén R, Cameán AM, Jos A, Prieto AI.   +4 more
europepmc   +1 more source

Toxicokinetic-Oriented Assessment of Nepetalactone Using In Silico ADMET Modeling, In Vitro Rat and Human Liver Microsomes, and UHPLC-MS/MS Metabolite Characterization. [PDF]

Toxics
Stoica NB, Cascajosa-Lira A, Morea A, Catunescu GM, Hornedo-Ortega R, Guzmán-Guillén R.   +5 more
europepmc   +1 more source

Application of In Silico QSAR and Molecular Docking Studies to a Series of Xanthine-Based Analogues and Design, Synthesis and Pharmacological Evaluation of Identified New Potential Selective MAO-B Inhibitors. [PDF]

Pharmaceuticals (Basel)
Mitkov Y, Mateev E, Valkova I, Kostov S, Kondeva-Burdina M, Zlatkov A.   +5 more
europepmc   +1 more source

Development of Novel Pegylated Imidazobenzodiazepines Targeting α5 GABAA Receptors for Anxiety: A Comparative Prodrug and Metabolite Study. [PDF]

ACS Chem Neurosci
Toriola MA, Kowalczyk ET, Medubi KM, Meyer MJ, Fernando MRT, Scholze P, Premananda N, Harrington SG, Barkley BR, Webb DA, Arnold LA.   +10 more
europepmc   +1 more source

IV-EVE: EVE for Injection-ADME, Pharmacokinetic and Toxicological Evaluation for Novel Deciparticle EVE Formulation. [PDF]

Biomedicines
Chang WH, Chang N, Min SH, Lopp JM, Hoff R, Hoque T, Trieu V, Lee C.   +7 more
europepmc   +1 more source