Results 191 to 200 of about 96,126 (327)

Identification of In Vitro Metabolites of Amoxicillin in Human Liver Microsomes by LC–ESI/MS [PDF]

open access: hybrid, 2014
Małgorzata Szultka‐Młyńska   +3 more
openalex   +1 more source

Enteric Nervous System Damage by Food Contaminants: A Pathway to Neurodegeneration?

open access: yesComprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 3, May 2026.
ABSTRACT The enteric nervous system (ENS), a key component of the gut–brain axis, has emerged as a critical player in the pathogenesis of Parkinson's disease (PD). It is the first neural system exposed to food contaminants (FCs)—a diverse group of ubiquitous toxic compounds fortuitously present in food derived from production, processing, storage, or ...
Helena Ramos   +3 more
wiley   +1 more source

Structure-Based Drug Discovery of Non-SAM-Mimetic Bisubstrate Inhibitors against Nicotinamide <i>N</i>‑Methyltransferase. [PDF]

open access: yesACS Med Chem Lett
Yoshida S   +7 more
europepmc   +1 more source

Influence of the CYP2D6*10 allele on the metabolism of mexiletine by human liver microsomes [PDF]

open access: bronze, 2001
Chiaki Senda   +7 more
openalex   +1 more source

Dexamethasone‐Mediated Regulation of CYP3A4 and UGTs in Human Hepatoma HuH‐7 Cells

open access: yesFundamental &Clinical Pharmacology, Volume 40, Issue 3, May 2026.
ABSTRACT Background The application of human hepatic cell lines to early drug discovery and development instead of human primary hepatocytes (HPHs) has been limited because of the low level of drug‐metabolizing enzymes (DMEs). Objective The study aimed to evaluate the effects of dexamethasone (DEX) treatment on DME expression, activities, and ...
Hana Yu   +4 more
wiley   +1 more source

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