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Potential induction of the relative mRNA expression levels of CYP450 by Zhicaowu-Hezi (Aconiti kusnezoffii radix preparata and <i>Terminalia chebula</i> Retz.). [PDF]
Front PharmacolZhu J +8 more
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Naunyn-Schmiedebergs Archiv f�r Experimentelle Pathologie und Pharmakologie, 1965
Various methods of disrupting liver cells and preparing microsomes were studied. The quality and yield of the microsomes in the preparations was judged by the NADPH-dependent N- and p-hydroxylation of N-ethylaniline, protein content, and cyanide-sensitive respiration.
Hermann G. Kampffmeyer +2 more
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Various methods of disrupting liver cells and preparing microsomes were studied. The quality and yield of the microsomes in the preparations was judged by the NADPH-dependent N- and p-hydroxylation of N-ethylaniline, protein content, and cyanide-sensitive respiration.
Hermann G. Kampffmeyer +2 more
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Microsomal metabolism of fluoroanilines
Xenobiotica, 19891. The microsomal, cytochrome P-450-dependent metabolism of fluoroanilines was studied using 19F-n.m.r. and also by a chemical assay for the hydroxy derivatives. 2. 2-Fluoro- and 3-fluoroaniline were preferentially hydroxylated at the para-position. 3. 4-Fluoroaniline was both p- and o-hydroxylated to a significant extent. 4.
Rietjens, I.M.C.M., Vervoort, J.
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Experientia, 1978
Studies which indicate the fusion of rat liver microsomal vesicles show that the rate of fusion of microsomal vesicles, as revealed by electron microscopic examinations, is dependent on the fusion temperature and the amount of detergent present in the microsomal suspension.
H. U. Schulze, Liliane Pop
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Studies which indicate the fusion of rat liver microsomal vesicles show that the rate of fusion of microsomal vesicles, as revealed by electron microscopic examinations, is dependent on the fusion temperature and the amount of detergent present in the microsomal suspension.
H. U. Schulze, Liliane Pop
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Effect of thiourea on microsomal oxidation alcohols and associated microsomal functions [PDF]
Biochemistry, 1979 Thiourea and diethylthiourea, two compounds which react with hydroxyl radicals, inhibited NADPH-dependent microsomal oxidation of ethanol and 1-butanol. Inhibition by both compounds was more effective in the presence of the catalase inhibitor, azide.
Elisa Dicker +3 more
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Microsomal metabolism of picene
Chemico-Biological Interactions, 1988Picene, a polycyclic aromatic hydrocarbon (PAH) of environmental relevance has recently been predicted to be carcinogenic, based on quantum mechanical calculation, although in several animal studies no carcinogenicity could be detected. In order to find out if the metabolism of this PAH can provide an explanation for its lack of carcinogenicity, picene
P. Petrovic +4 more
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2009
Proteomic profiling of subcellular compartments has many advantages over traditional proteomic approaches using whole cell lysates as it allows for detailed proteome analysis of a specific organelle and corresponding functional characteristics. The microsome is a critical, membranous compartment involved in the synthesis, sorting, and secretion of ...
Diana M, Wong, Khosrow, Adeli
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Proteomic profiling of subcellular compartments has many advantages over traditional proteomic approaches using whole cell lysates as it allows for detailed proteome analysis of a specific organelle and corresponding functional characteristics. The microsome is a critical, membranous compartment involved in the synthesis, sorting, and secretion of ...
Diana M, Wong, Khosrow, Adeli
openaire +2 more sources