Results 81 to 90 of about 49,138 (216)
Comparative Metabolism of Cinobuafgin in Liver Microsomes from Mouse,Rat,Dog,Pig,Monkey and Human
, 2010 Cinobufagin (CBG), a major bioactive component of Traditional Chinese Medicine Chan-Su with digoxin-like structure, has been reported with Na+-K+-ATPase inhibitory effects and outstanding antitumor activities.
梁思成 +4 more
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Preparation of ER microsomes from Arabidopsis thaliana [PDF]
Microsomes are vesicles derived from the endoplasmic reticulum (ER) when cells are broken down in the lab. These microsomes are a valuable tool to study a variety of ER functions such as protein and lipid synthesis in vitro.
Kriechbaumer, Verena
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Characterization Of In Vitro Metabolism of Brucine Using Human Liver Microsomes
, 2010 Background. Brucine, one of the bitter alkaloids isolated from Chinese folk medicine Strychnos nux-vomica L. (Loganiaceae), is known as an effective analgesic and anti- inflammatory agent for relieving arthritic and traumatic pain.
房中则 +4 more
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Metabolic Difference of CZ48 in Human and Mouse Liver Microsomes
, 2012 CZ48, chemically camptothecin-20-O-propionate hydrate, is currently under clinical investigation. The kinetics of the metabolite camptothecin (CPT) formation and of CZ48 depletion in mouse and human liver microsomes in the presence or absence of NADPH ...
Xing Liu +4 more
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In Vitro Metabolic Study of Boc5 in human tissues and Animal Liver Microsomes
, 2009 As the first nonpeptidic agonist of glucagon-like peptide 1 receptor, Boc5 can invoke sustained glycemic control and weight loss in diabetic C57BL/6J mice, and has become a promising hit compound for antidiabetic drug. Boc5 displays good efficiency via i.
梁思成 +4 more
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, 2017 Use of the immunosuppressant mycophenolic acid (MPA) in cats is limited because MPA elimination depends on glucuronidation, which is deficient in cats.
Slovak, J E, Mealey, K, Court, M H
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Characterization of in vitro bioactivation of rutaecarpine in human liver microsomes (HLMs)
, 2010 Reactive drug metabolites have been always considered mediators of drug-induced toxicities and risk would increase with the increasing reactive metabolites.
房中则, Ling Yang, 杨凌
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, 1988 The capacity of human, rabbit and rat liver microsomes and purified isozymes of cytochrome P450 to metabolize theophylline has been assessed. In all three species the 8-hydroxylation of theophylline to 1,3-dimethyluric acid (1,3-DMU) was the major ...
J O Miners +4 more
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Scheme for metabolites of 2a observed with human liver microsomes.
, 2018 Scheme for metabolites of 2a observed with human liver microsomes.
Alfin D. N. Vaz (172262) +8 more
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Vitamin K dependent formation of γ-carboxyglutamate residues in tumor microsomes
, 1982 Vitamin K stimulated the incorporation of 14C into proteins when microsomes from melanoma, mammary gland, mast cell and lymphoma tumors were incubated with Na214CO3.
Bell, Robert G. +3 more
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