Results 61 to 70 of about 56,066 (278)
Animal Models and Experimental Medicine, EarlyView.Due to the complex pathophysiology of aortic valve disease (AVD) and the resulting lack of effective pharmacotherapy, existing animal models are valuable research tools, but each has its own strengths and limitations. This review systematically surveys the major AVD models, compares their induction methods, pathological features, advantages and ...
Liya Hou +4 more
wiley +1 more source
Synthesis and turnover of cerebroside sulfate of myelin in adult and developing rat brain
Journal of Lipid Research, 1974 The turnover of cerebroside sulfate (sulfatide) was followed in both microsomal and myelin fractions of developing and adult rat brains after an intracerebral injection of Na235SO4.
Firoze B. Jungalwala
doaj +1 more source
Biphenyl Hydroxylation by Vole Hepatic Microsomes [PDF]
, 1981 Metabolism of biphenyl by meadow voles (Microtus montanus) liver microsomes was studied by gas liquid chromatography. The microsomal biphenyl hydroxylation of Swiss Webster mice (outbred) was also investigated to provide a species comparison.
Makary, Moheb H.
core +1 more source
Phospholipids and acyl groups of subcellular membrane fractions from human intracranial tumors
Journal of Lipid Research, 1974 The phospholipids from subcellular fractions of human intracranial tumors were examined. For comparison, microsomes were isolated from a fetal human brain and from the gray matter of adult human brains.
G.Y. Sun, B.S. Leung
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The Journal of Cell Biology, 1956 Rat liver, liver homogenates, and microsome fractions separated therefrom were examined systematically in the electron microscope in sections of OsO4-fixed, methacrylate-embedded tissue and pellets. It was found that most microsomes are morphologically identical with the rough surfaced elements of the endoplasmic reticula of hepatic ...
G E, PALADE, P, SIEKEVITZ
openaire +2 more sources
Functional Reconstitution of Membrane Proteins Derived From Eukaryotic Cell-Free Systems
Frontiers in Pharmacology, 2019 Cell-free protein synthesis (CFPS) based on eukaryotic Sf21 lysate is gaining interest among researchers due to its ability to handle the synthesis of complex human membrane proteins (MPs).
Srujan Kumar Dondapati +6 more
doaj +1 more source
Epoxidation of aldrin by rainbow trout liver microsomes
Assay conditions and analytical methods established for the study of epoxidation of the insecticides aldrin and heptachlor, by rat liver microsomes have been employed to study the same reaction catalyzed by trout liver microsomes.
Chan, Timothy Ming-wai
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Pharmaceutics, 2017 Uridine diphosphate-glucuronosyltransferases (UGTs) are phase 2 conjugation enzymes mainly located in the endoplasmic reticulum (ER) of the liver and many other tissues, and can be recovered in artificial ER membrane preparations (microsomes).
Yuejian Liu, Michael W. H. Coughtrie
doaj +1 more source
Pharmaceuticals, 2014 In general, prodrugs are developed to circumvent deficiencies associated with the absorption, distribution, metabolism, excretion or toxicological (ADMET) profile associated with the active drug.
Paul Matthew O'Byrne +3 more
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Molecules, 2012 Isoliensinine, a natural phenolic bisbenzyltetrahydroisoquinoline alkaloid, has received considerable attention for its potential biological effects such as antioxidant and anti-HIV activities.
Su Zeng +3 more
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