Results 41 to 50 of about 49,138 (216)

Enzymatic synthesis of cytidine diphosphate diglyceride

open access: yesJournal of Lipid Research, 1966
Evidence is presented for the enzymatic formation of cytidine diphosphate diglyceride in microsomal preparations from guinea pig liver according to the reaction:CTP + phosphatidic acid ⇌ CDP-diglyceride + P—O—P.Conditions have been found in which the ...
James R. Carter, Eugene P. Kennedy
doaj   +1 more source

Inhibition of in vitro metabolism of testosterone in human, dog and horse liver microsomes to investigate species differences.

open access: yes, 2015
Testosterone hydroxylation was investigated in human, canine and equine liver microsomes and in human and canine single CYPs. The contribution of the CYP families 1, 2 and 3 was studied using chemical inhibitors. Testosterone metabolites were analyzed by
Mevissen, Meike, Zielinski, Jana
core   +1 more source

Effect of dietary monosodium glutamate on trans fat-induced nonalcoholic fatty liver disease

open access: yesJournal of Lipid Research, 2009
The effects of dietary monosodium glutamate (MSG) on trans-fatty acid (TFA)-induced nonalcoholic fatty liver disease (NAFLD) are addressed in an animal model.
Kate S. Collison   +9 more
doaj   +1 more source

A Comparative Study of Phase I and II Hepatic Microsomal Biotransformation of Phenol in Three Species of Salmonidae: Hydroquinone, Catechol, and Phenylglucuronide Formation

open access: yesFishes
The in vitro biotransformation of phenol at 11 °C was studied using pre-spawn adult rainbow (Oncorhynchus mykiss) (RBT), brook (Salvelinus fontinalis) (BKT), and lake trout (Salvelinus namaycush) (LKT) hepatic microsomal preparations.
Richard C. Kolanczyk   +3 more
doaj   +1 more source

Synthesis and turnover of cerebroside sulfate of myelin in adult and developing rat brain

open access: yesJournal of Lipid Research, 1974
The turnover of cerebroside sulfate (sulfatide) was followed in both microsomal and myelin fractions of developing and adult rat brains after an intracerebral injection of Na235SO4.
Firoze B. Jungalwala
doaj   +1 more source

Electrochemical Probing of Human Liver Subcellular S9 Fractions for Drug Metabolite Synthesis

open access: yesMetabolites
Human liver subcellular fractions, including liver microsomes (HLM), liver cytosol fractions, and S9 fractions, are extensively utilized in in vitro assays to predict liver metabolism.
Daphne Medina   +4 more
doaj   +1 more source

Phospholipids and acyl groups of subcellular membrane fractions from human intracranial tumors

open access: yesJournal of Lipid Research, 1974
The phospholipids from subcellular fractions of human intracranial tumors were examined. For comparison, microsomes were isolated from a fetal human brain and from the gray matter of adult human brains.
G.Y. Sun, B.S. Leung
doaj   +1 more source

LIVER MICROSOMES [PDF]

open access: yesThe Journal of Cell Biology, 1956
Rat liver, liver homogenates, and microsome fractions separated therefrom were examined systematically in the electron microscope in sections of OsO4-fixed, methacrylate-embedded tissue and pellets. It was found that most microsomes are morphologically identical with the rough surfaced elements of the endoplasmic reticula of hepatic ...
G. E. Palade, P. Siekevitz
openaire   +1 more source

Functional Reconstitution of Membrane Proteins Derived From Eukaryotic Cell-Free Systems

open access: yesFrontiers in Pharmacology, 2019
Cell-free protein synthesis (CFPS) based on eukaryotic Sf21 lysate is gaining interest among researchers due to its ability to handle the synthesis of complex human membrane proteins (MPs).
Srujan Kumar Dondapati   +6 more
doaj   +1 more source

PANCREATIC MICROSOMES [PDF]

open access: yesThe Journal of Cell Biology, 1956
The pancreatic exocrine cell of the guinea pig has a voluminous endoplasmic reticulum distinguished by extensive association with small, dense particles, and by its orderly disposition in the basal region of the cell. In addition to the small, (∼15 mµ), dense particles attached to the limiting membrane of the endoplasmic reticulum ...
G. E. Palade, P. Siekevitz
openaire   +1 more source

Home - About - Disclaimer - Privacy