Results 71 to 80 of about 49,138 (216)

Metabolic activation of 1,1-dichloroethylene by mouse lung and liver microsomes

open access: yes, 1987
1,1-Dichloroethylene (1,1-DCE) causes lung and liver necrosis in mice. Covalent binding of [14C] 1,1-DCE to isolated lung and liver microsomes from CD-1 mice required NADPH and was strongly inhibited by carbon monoxide.
P. G. Forkert, W. J. Racz, M. Hofley
core   +1 more source

Über den Steringehalt pflanzlicher Mikrosomen

open access: yesCHIMIA, 1975
The composition of microsomal lipids from Spirodela oligorrhiza L., Lactuca sativa L., and Allium porrum L. plants was investigated. Contamination by chloroplast lipids was calculated and eliminated, giving the lipids of “chloroplast-free microsomes ...
W. Eichenberger
doaj   +1 more source

rflaA:Ova is differently processed in mDC-derived microsomes.

open access: yes, 2014
Microsomes were isolated from unstimulated BALB/c mDC and used for digestion of rOva and rflaA:Ova (A+B). Protein amounts equimolar to 5 µg rOva (5 µg rOva, 8.5 µg rflaA:Ova) were digested for each indicated time point.
Masako Toda (587290)   +15 more
core   +1 more source

Biochemical research elucidating metabolic pathways in Pneumocystis*

open access: yesParasite, 2010
Advances in sequencing the Pneumocystis carinii genome have helped identify potential metabolic pathways operative in the organism. Also, data from characterizing the biochemical and physiological nature of these organisms now allow elucidation of ...
Kaneshiro E.S.
doaj   +1 more source

Preparation of brain microsomes with cytochrome P450 activity using calcium aggregation method

open access: yes, 1990
Microsomes have been conventionally prepared by centrifugation of the postmitochondrial supernatant at 100,000g using an ultracentrifuge. Liver microsomes have been prepared by low speed centrifugation following sedimentation of the microsomal membranes ...
Anandatheerthavarada, Hindupur K.   +1 more
core   +1 more source

3-hydroxy-3-methylglutaryl coenzyme A reductase in human liver microsomes: active and inactive forms and cross-reactivity with antibody against rat liver enzyme.

open access: yesJournal of Lipid Research, 1984
3-Hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, the enzyme catalyzing the rate-limiting step in cholesterol biosynthesis, exists in one active (dephosphorylated) and one inactive (phosphorylated) form in liver microsomes obtained from several ...
B Angelin   +4 more
doaj   +1 more source

Comparative Metabolism of Cinobufagin in Liver Microsomes from Mouse, Rat, Dog, Pig, Monkey and Human

open access: yes, 2010
Cinobufagin (CBG), a major bioactive component of Traditional Chinese Medicine ChanSu with digoxin-like structure, has been reported with Na+-K+-ATPase inhibitory effects and outstanding antitumor activities.
梁思成   +4 more
core  

A new pathway for phosphatidylserine synthesis in rat liver microsomes

open access: yes, 1988
It has been shown that the phosphate moiety of glycerophosphate is incorporated into phosphatidylserine of rat liver microsomes, but not of mitochondria. The reaction is dependent on CMP.
Baraǹska, Jolanta, Jolanta Baraǹska
core   +1 more source

Pyridine nucleotide regulation of hepatic endoplasmic reticulum calcium uptake

open access: yesPhysiological Reports, 2019
Pyridine nucleotides serve an array of intracellular metabolic functions such as, to name a few, shuttling electrons in enzymatic reactions, safeguarding the redox state against reactive oxygen species, cytochrome P450 (CYP) enzyme detoxification ...
Xudong Wang   +2 more
doaj   +1 more source

Fate of linoleic, arachidonic, and docosa-7,10,13,16-tetraenoic acids in rat testicles

open access: yesJournal of Lipid Research, 1973
A comparative study was made on the fate of linoleic, arachidonic, and docosa-7,10,13,16-tetraenoic acids in various subcellular fractions of liver and testis from rats of different ages.
Sixta Ayala   +4 more
doaj   +1 more source

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