Results 31 to 40 of about 44,447 (249)

Clinically Relevant Outcome Measures in Women With Adrenoleukodystrophy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Adrenoleukodystrophy is a rare inherited peroxisomal disease caused by pathogenic variants in the ABCD1 gene located on the X chromosome. Although the most severe central nervous system and adrenal complications typically affect only men with adrenoleukodystrophy, the majority of women develop myeloneuropathy symptoms in adulthood.
Chenwei Yan, Elizabeth I. Pierpont, Amena S. Fine, Reena V. Kartha   +3 more
wiley   +1 more source

Co effect on rapid solidification microstructure transition of highly undercooled copper alloys

Journal of Materials Research and Technology, 2023
The present work systematically studied nonequilibrium solidification microstructure and its morphology evolution with undercooling of Cu60Ni40 binary alloy and Cu60Ni35Co5 ternary alloy, and the characteristic undercooling degree of alloy evolution was ...
Xiaolong Xu, Qi Wu, Yongchao Hao, Li Wu, Yuhong Zhao, Hua Hou   +5 more
doaj   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

A review: applications of the phase field method in predicting microstructure and property evolution of irradiated nuclear materials

npj Computational Materials, 2017
Complex microstructure changes occur in nuclear fuel and structural materials due to the extreme environments of intense irradiation and high temperature.
Yulan Li, Shenyang Hu, Xin Sun, Marius Stan   +3 more
doaj   +1 more source

Hot extrusion characteristics and technique optimization for superalloy 617B tube

工程科学学报, 2019
Nickel-base superalloy 617B is one of the most promising candidates for superheater and reheater pipes of advanced ultra-supercritical (AUSC) power plants.Hot extrusion is a key process during the manufacturing of superalloy 617B pipes.However, the high ...
JIANG He, DONG Jian-xin, ZHANG Mai-cang
doaj   +1 more source

In-situ observation microstructure evolution and growth kinetics of lamellar γ phases in Ti44Al alloy during heat treatment

Journal of Materials Research and Technology, 2020
To study mechanism of microstructure evolution in TiAl based alloys during heat treatment, Ti44Al alloy was heat treated at 1240 °C for 0.5/1.0/2.0/2.5/3.0/5.0/7.0 h before being quenched in water. Chemical composition, phase component and microstructure
Yangli Liu, Xiang Xue, Hongze Fang, Yingmei Tan, Ruirun Chen, Hongzhi Cui, Yanqing Su, Jingjie Guo   +7 more
doaj   +1 more source

Multi-Phase Field Method for Solidification Microstructure Evolution for a Ni-Based Alloy in Wire Arc Additive Manufacturing

Metals, 2022
Wire arc additive manufacturing achieves high efficiency and low costs by using a melting wire for directional depositions. Thermal analyses and the finite element method have been applied to predict residual stress and the deformation of fabricated ...
Sukeharu Nomoto, Masahiro Kusano, Houichi Kitano, Makoto Watanabe   +3 more
doaj   +1 more source

Thermomechanical evolution of a microstructure [PDF]

Quarterly of Applied Mathematics, 1994
A nonisothermal microstructure evolution model, governed by a Helmholtz free energy which need not be convex as a function of deformations, is formulated by using a convexified geometry proposed already in [13]. A multidimensional but scalar case is treated.
Hoffmann, Karl-Heinz, Roubíček, Tomáš   +1 more
openaire   +2 more sources

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

Prediction of Mean Grain Size Evolution during the Forging of IN718 Turbine Disc

MATEC Web of Conferences, 2016
The microstructure evolution during the cogging, upsetting and hot die forging in the manufacture of IN718 turbine disc has been predicted through coupling the microstructure evolution prediction system developed with a commercial finite element software.
Haiyan Zhang, Shihong Zhang, Ming Cheng
doaj   +1 more source