Results 91 to 100 of about 257,791 (336)

Microtubule-associated protein tau is associated with the resistance to docetaxel in prostate cancer cell lines

open access: yesResearch and Reports in Urology, 2017
Jian Yang,1,2,* Yang Yu,1,* Wei Liu,2 Zhi Li,2 Zhongqing Wei,2 Rongjiang Jiang1,2 1The Second Clinical Medical College of Nanjing Medical University, 2Department of Urology, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu ...
Yang J   +6 more
doaj  

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

open access: yesAdvanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi   +4 more
wiley   +1 more source

Retroviruses and microtubule-associated motor proteins

open access: yesCellular Microbiology, 2017
Retroviruses are obligate intracellular parasites of eukaryotic cells. After reverse transcription, the viral DNA contained in the preintegration complex is delivered to the nucleus of the host cell, where it integrates. Before reaching the nucleus, the incoming particle and the preintegration complex must travel throughout the cytoplasm. Likewise, the
openaire   +3 more sources

MAP4 (microtubule-associated protein 4) [PDF]

open access: yesAtlas of Genetics and Cytogenetics in Oncology and Haematology, 2011
Review on MAP4 (microtubule-associated protein 4), with data on DNA, on the protein encoded, and where the gene is implicated.
Murga, Penas EM, Dierlamm, J
openaire   +2 more sources

Functional coupling of microtubules to membranes - implications for membrane structure and dynamics [PDF]

open access: yes, 2012
The microtubule network dictates much of the spatial patterning of the cytoplasm, and the coupling of microtubules to membranes controls the structure and positioning of organelles and directs membrane trafficking between them.
Stephens, David J
core   +2 more sources

RhoA and Rac1 as Mechanotransduction Mediators in Colorectal Cancer

open access: yesAdvanced Biology, EarlyView.
Analysing RhoA and Rac1 protein levels in Colorectal cancer (CRC) samples under mechanical strain highlights their potential as diagnostic markers. Monitoring their activity could offer valuable insights into how cancer spreads, paving the way for new approaches to better understand and diagnose colorectal cancer.
Sharda Yadav   +5 more
wiley   +1 more source

Plant and mouse EB1 proteins have opposite intrinsic properties on the dynamic instability of microtubules

open access: yesBMC Research Notes, 2020
Objective Most eukaryotic cells contain microtubule filaments, which play central roles in intra-cellular organization. However, microtubule networks have a wide variety of architectures from one cell type and organism to another.
Arthur T. Molines   +3 more
doaj   +1 more source

Regulation of Microtubule Dynamics in Axon Regeneration: Insights from C. elegans. [PDF]

open access: yes, 2016
The capacity of an axon to regenerate is regulated by its external environment and by cell-intrinsic factors. Studies in a variety of organisms suggest that alterations in axonal microtubule (MT) dynamics have potent effects on axon regeneration.
CHISHOLM, Andrew, Tang, Ngang
core   +2 more sources

The Regulation of Trace Metal Elements in Cancer Ferroptosis

open access: yesAdvanced Biology, EarlyView.
The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang   +5 more
wiley   +1 more source

Identification of microtubule-associated proteins in the centrosome, spindle, and kinetochore of the early Drosophila embryo. [PDF]

open access: yes, 1989
We have developed affinity chromatography methods for the isolation of microtubule-associated proteins (MAPs) from soluble cytoplasmic extracts and have used them to analyze the cytoskeleton of the early Drosophila embryo.
Alberts, BM, Field, CM, Kellogg, DR
core  

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