Nemitin, a novel Map8/Map1s interacting protein with Wd40 repeats. [PDF]
PLoS ONE, 2012 In neurons, a highly regulated microtubule cytoskeleton is essential for many cellular functions. These include axonal transport, regional specialization and synaptic function.
Wei Wang +12 more
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Rice microtubule‐associated protein IQ67‐DOMAIN14 regulates rice grain shape by modulating microtubule cytoskeleton dynamics [PDF]
, 2020 Cortical microtubule (MT) arrays play a critical role in plant cell shape determination by defining the direction of cell expansion. As plants continuously adapt to ever‐changing environmental conditions, multiple environmental and developmental inputs ...
De Rybel, Bert +4 more
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The mitotic spindle protein CKAP2 potently increases formation and stability of microtubules
eLife, 2022 Cells increase microtubule dynamics to make large rearrangements to their microtubule cytoskeleton during cell division. Changes in microtubule dynamics are essential for the formation and function of the mitotic spindle, and misregulation can lead to ...
Thomas S McAlear, Susanne Bechstedt
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Microtubule-Associated Proteins: Structuring the Cytoskeleton [PDF]
Trends in Cell Biology, 2019 Microtubule-associated proteins (MAPs) were initially discovered as proteins that bind to and stabilize microtubules. Today, an ever-growing number of MAPs reveals a more complex picture of these proteins as organizers of the microtubule cytoskeleton that have a large variety of functions.
Cristopher Villablanca +6 more
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Characterization and functional analysis of the potato pollen-specific microtubule-associated protein SBgLR in tobacco. [PDF]
PLoS ONE, 2013 Microtubule-associated proteins play a crucial role in the regulation of microtubule dynamics, and are very important for plant cell and organ development.
Chen Liu, Xin Qi, Qian Zhao, Jingjuan Yu
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Multifunctional Microtubule-Associated Proteins in Plants [PDF]
Frontiers in Plant Science, 2016 Microtubules (MTs) are involved in key processes in plant cells, including cell division, growth and development. MT-interacting proteins modulate MT dynamics and organization, mediating functional and structural interaction of MTs with other cell structures.
Jana eKrtková +4 more
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Autoregulatory control of microtubule binding in doublecortin-like kinase 1
eLife, 2021 The microtubule-associated protein, doublecortin-like kinase 1 (DCLK1), is highly expressed in a range of cancers and is a prominent therapeutic target for kinase inhibitors. The physiological roles of DCLK1 kinase activity and how it is regulated remain
Regina L Agulto +8 more
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Microtubule-associated proteins of neurons. [PDF]
The Journal of cell biology, 1983 Microtubule-associated proteins (MAP) have been identified in cultures of rat sympathetic neurons. In all of the experiments performed here, the cultures consisted of greater than 97% neurons. 26 proteins were identified in these neuronal cultures that (a) remained associated with cytoskeletons prepared with a Triton X-100-containing microtubule ...
J T Kurdyla, M M Black
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The MAP1 family of microtubule-associated proteins [PDF]
Genome Biology, 2006 MAP1-family proteins are classical microtubule-associated proteins (MAPs) that bind along the microtubule lattice. The founding members, MAP1A and MAP1B, are predominantly expressed in neurons, where they are thought to be important in the formation and development of axons and dendrites.
Shelley Halpain, Leif Dehmelt
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Neuronal deletion of GSK3beta increases microtubule speed in the growth cone and enhances axon regeneration via CRMP-2 and independently of MAP1B and CLASP2 [PDF]
, 2014 BACKGROUND: In the adult central nervous system, axonal regeneration is abortive. Regulators of microtubule dynamics have emerged as attractive targets to promote axonal growth following injury as microtubule organization is pivotal for growth cone ...
Liz, Márcia A. +12 more
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