Results 71 to 80 of about 49,535,711 (155)

Data supporting the inability of indomethacin to induce autophagy in U251 glioma cells

Data in Brief, 2017
Autophagy, a catabolic process involving intracellular degradation of unnecessary or dysfunctional cellular components through the lysosomal machinery, could act as a prosurvival, as well as a cytotoxic mechanism (Parzych and Klionsky, 2014) [1 ...
Aleksandar Pantovic, Katarina Arsikin, Milica Kosic, Biljana Ristic, Vladimir Trajkovic, Ljubica Harhaji-Trajkovic   +5 more
doaj   +1 more source

Ubiquitin, p62, and Microtubule-Associated Protein 1 Light Chain 3 in Cardiomyopathy. [PDF]

Circ Rep, 2023
Eto R, Kawano H, Matsuyama-Matsuu M, Matsuda K, Ueki N, Nakashima M, Okano S, Ishijima M, Kawakatsu M, Watanabe J, Yoshimuta T, Ikeda S, Maemura K.   +12 more
europepmc   +1 more source

ATG9A-dependent, LC3-independent autophagy curbs the immune system to protect against disease

Autophagy Reports
Selective autophagy is generally believed to require the conjugation of microtubule associated protein 1 light chain 3 (LC3) proteins (or other autophagy-related 8 [ATG8] family members) on the inner phagophore leaflet to enable the recruitment of cargo ...
Dario Priem, Mathieu JM Bertrand
doaj   +1 more source

A dynamic microtubule cytoskeleton directs medial actomyosin function during tube formation [PDF]

, 2014
The cytoskeleton is a major determinant of cell-shape changes that drive the formation of complex tissues during development. Important roles for actomyosin during tissue morphogenesis have been identified, but the role of the microtubule cytoskeleton is
Blanchard, Guy B., Adams, Richard J., Röper, Katja, Booth, Alexander J. R., Booth, Alexander J.R.   +4 more
core   +1 more source

Intracellular Toxic Advanced Glycation End-Products in 1.4E7 Cell Line Induce Death with Reduction of Microtubule-Associated Protein 1 Light Chain 3 and p62. [PDF]

Nutrients, 2022
Takata T, Sakasai-Sakai A, Takeuchi M.
europepmc   +1 more source

Microtubule-associated protein tau is associated with the resistance to docetaxel in prostate cancer cell lines

, 2017
Jian Yang,1,2,* Yang Yu,1,* Wei Liu,2 Zhi Li,2 Zhongqing Wei,2 Rongjiang Jiang1,2 1The Second Clinical Medical College of Nanjing Medical University, 2Department of Urology, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu ...
Yang J, Li Z, Wei ZQ, Jiang R, Yu Y, Liu W   +5 more
core  

Structural studies on protein scaffolds related to muscle physiology and disease : the titin filament, its associated component MuRF-1 and nuclear LAP2[alpha] [PDF]

, 2006
The titin molecule has a length of overµm and functions as a colossal protein scaffold in the muscle sarcomere. Up to 90% of its total mass is composed of repetitive immunoglobulin (Ig) and fibronectin (FnIII) domains that form linear tandems ...
Mrosek, Michael Christian
core   +1 more source

Bauhinia championii flavone inhibits apoptosis and autophagy via the PI3K/Akt pathway in myocardial ischemia/reperfusion injury in rats

Drug Design, Development and Therapy, 2015
Jie Jian,1,* Feifei Xuan,2,* Feizhang Qin,2 Renbin Huang21Department of Pharmacology, Guilin Medical University, Guilin, Guangxi, 2Department of Pharmacology, Guangxi Medical University, Nanning, People’s Republic of China*These authors contributed
Jian J, Xuan FF, Qin FZ, Huang RB
doaj  

Mitophagy in hepatocytes: Types, initiators and role in adaptive ethanol metabolism

Liver Research, 2018
Mitophagy (mitochondrial autophagy) in hepatocytes is an essential quality control mechanism that removes for lysosomal digestion damaged, effete and superfluous mitochondria. Mitophagy has distinct variants.
John J. Lemasters, Zhi Zhong
doaj   +1 more source

C-Nap1, a novel centrosomal coiled-coil protein and candidate substrate of the cell cycle-regulated protein kinase Nek2 [PDF]

, 1998
Nek2 (for NIMA-related kinase 2) is a mammalian cell cycle-regulated kinase structurally related to the mitotic regulator NIMA of Aspergillus nidulans.
Fry, A. M., Erich A. Nigg, Stierhof, Y. D., Mayor, T., Y. D. Stierhof (7653686), Tanaka, K., Nigg, E. A., Meraldi, P., Thibault Mayor, A. M. Fry (7651490), E. A. Nigg (7651493), Kayoko Tanaka, Andrew M. Fry, P. Meraldi (7653683), K. Tanaka (1500880), Patrick Meraldi, York-Dieter Stierhof, T. Mayor (7653680)   +17 more
core   +1 more source