Results 41 to 50 of about 1,205,418 (341)
Genes of ancient microtubule-stabilizing proteins traveled through pre-Cambrian Echinoidea to advanced life forms of dry land and ended up in the human genome as the fusion oncogenes-oncoproteins eml1/EML1-abl/ABL, and eml4/EML4-alk/ALK [PDF]
Invertebrate Survival Journal, 2016 The genes eml1/4 of the Echinodermata microtubule-stabilizing gene product-like 1/4 proteins EML1/4 of the sea cucumbers (Holothuroidea) traveled through the evolutionary scale up to the human genome.
JG Sinkovics
doaj +2 more sources
The evolution and diversification of plant microtubule-associated proteins.
The Plant Journal, 2013 Plant evolution is marked by major advances in structural characteristics that facilitated the highly successful colonization of dry land. Underlying these advances is the evolution of genes encoding specialized proteins that form novel microtubular ...
J. Gardiner
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Interaction of estramustine phosphate with microtubule‐associated proteins [PDF]
FEBS Letters, 1985 We have reported [(1984) Cancer Res., in press] that estramustine phosphate inhibits microtubule assembly and disassembled preformed microtubules. We now present evidence that estramustine phosphate inhibits microtubule assembly by binding to the microtubule‐associated proteins.
Margareta Wallin +2 more
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Journal of Biological Chemistry, 2012 Background: The microtubule-associated proteins tau and MAP2 are dephosphorylated by PP2A, a major brain Ser/Thr phosphatase. Results: Identification of a common PP2A-binding motif in tau and MAP2. Conclusion: Soluble tau and MAP2 can compete for binding
J. Sontag +4 more
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Evidence that griseofulvin binds to a microtubule associated protein [PDF]
FEBS Letters, 1977 We have recently shown that the anti-mitotic drug, griseofulvin, inhibits assembly of brain microtubules in vitro [l] . Similar data have been presented by Weber et al. [2] . Our earlier experiments indicated that griseofulvin inhibits microtubule assembly by preventing the association between tubulin and the microtubule associated proteins (MAPS ...
Roobol, A, Gull, K, Pogson, I
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Plant Methods, 2019 Background In the present work, we provide an account of structured illumination microscopy (SIM) imaging of fixed and immunolabeled plant probes. We take advantage of SIM, to superresolve intracellular structures at a considerable z-range and circumvent
T. Vavrdová +7 more
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Microtubule Regulation in Plants: From Morphological Development to Stress Adaptation
Biomolecules, 2023 Microtubules (MTs) are essential elements of the eukaryotic cytoskeleton and are critical for various cell functions. During cell division, plant MTs form highly ordered structures, and cortical MTs guide the cell wall cellulose patterns and thus control
An-Shan Hsiao, Ji-Ying Huang
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Autophagy in cancer and protein conformational disorders
FEBS Letters, EarlyView.Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
CCDC74A/B are K-fiber crosslinkers required for chromosomal alignment
BMC Biology, 2019 Background Spindle microtubule organization, regulated by microtubule-associated proteins, is critical for cell division. Proper organization of kinetochore fiber (K-fiber), connecting spindle poles and kinetochores, is a prerequisite for precise ...
Haining Zhou +7 more
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Role of Tau as a Microtubule-Associated Protein: Structural and Functional Aspects
Frontiers in Aging Neuroscience, 2019 Microtubules (MTs) play a fundamental role in many vital processes such as cell division and neuronal activity. They are key structural and functional elements in axons, supporting neurite differentiation and growth, as well as transporting motor ...
P. Barbier +8 more
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