New Insights Into Functions of IQ67-Domain Proteins
Frontiers in Plant Science, 2021 IQ67-domain (IQD) proteins, first identified in Arabidopsis and rice, are plant-specific calmodulin-binding proteins containing highly conserved motifs.
Chunyue Guo +3 more
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The MAP1 family of microtubule-associated proteins [PDF]
Genome Biology, 2006 MAP1-family proteins are classical microtubule-associated proteins (MAPs) that bind along the microtubule lattice. The founding members, MAP1A and MAP1B, are predominantly expressed in neurons, where they are thought to be important in the formation and development of axons and dendrites.
Halpain, S., Dehmelt, L.
openaire +3 more sources
Manipulation and quantification of microtubule lattice integrity
Biology Open, 2017 Microtubules are structural polymers that participate in a wide range of cellular functions. The addition and loss of tubulin subunits allows the microtubule to grow and shorten, as well as to develop and repair defects and gaps in its cylindrical ...
Taylor A. Reid +2 more
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Beyond uniformity: Exploring the heterogeneous and dynamic nature of the microtubule lattice
European Journal of Cell Biology, 2023 A fair amount of research on microtubules since their discovery in 1963 has focused on their dynamic tips. In contrast, the microtubule lattice was long believed to be highly regular and static, and consequently received far less attention.
Mariana Romeiro Motta +2 more
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Xenopus meiotic microtubule-associated interactome. [PDF]
PLoS ONE, 2010 In metazoan oocytes the assembly of a microtubule-based spindle depends on the activity of a large number of accessory non-tubulin proteins, many of which remain unknown. In this work we isolated the microtubule-bound proteins from Xenopus eggs.
Vincent Gache +6 more
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Genes of ancient microtubule-stabilizing proteins traveled through pre-Cambrian Echinoidea to advanced life forms of dry land and ended up in the human genome as the fusion oncogenes-oncoproteins eml1/EML1-abl/ABL, and eml4/EML4-alk/ALK [PDF]
Invertebrate Survival Journal, 2016 The genes eml1/4 of the Echinodermata microtubule-stabilizing gene product-like 1/4 proteins EML1/4 of the sea cucumbers (Holothuroidea) traveled through the evolutionary scale up to the human genome.
JG Sinkovics
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GTSE1 is a microtubule plus-end tracking protein that regulates EB1-dependent cell migration. [PDF]
PLoS ONE, 2012 The regulation of cell migration is a highly complex process that is often compromised when cancer cells become metastatic. The microtubule cytoskeleton is necessary for cell migration, but how microtubules and microtubule-associated proteins regulate ...
Massimilano Scolz +13 more
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CCDC74A/B are K-fiber crosslinkers required for chromosomal alignment
BMC Biology, 2019 Background Spindle microtubule organization, regulated by microtubule-associated proteins, is critical for cell division. Proper organization of kinetochore fiber (K-fiber), connecting spindle poles and kinetochores, is a prerequisite for precise ...
Haining Zhou +7 more
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Microtubule Regulation in Plants: From Morphological Development to Stress Adaptation
Biomolecules, 2023 Microtubules (MTs) are essential elements of the eukaryotic cytoskeleton and are critical for various cell functions. During cell division, plant MTs form highly ordered structures, and cortical MTs guide the cell wall cellulose patterns and thus control
An-Shan Hsiao, Ji-Ying Huang
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