Results 271 to 280 of about 63,482 (321)

Mannose Oligosaccharide‐Conjugated In Situ Pore‐Forming Injectable Hydrogels for Rheumatoid Arthritis Treatment by Reprogramming Macrophage Extracellular Vesicles

Small Methods, EarlyView.
Design of an injectable porous hydrogel modulating macrophages and their secreted EVs for joint defect repair in the pathology of rheumatoid arthritis. a) The solution containing HA and CS‐MOS, upon mixing with a crosslinker solution, undergoes porous hydrogel formation with the escape of generated CO₂ gas.
Anan Zhang, Yifan Ma, Yutong Liu, Shiyan Dong, Michelle Najarro Torres, Betty Y.S. Kim, Changsheng Liu, Lili Sun, Yuan Yuan, Wen Jiang   +9 more
wiley   +1 more source

The Rab7-Epg5 and Rab39-ema modules cooperatively position autophagosomes for efficient lysosomal fusions. [PDF]

Elife
Boda A, Balázs V, Nagy A, Hargitai D, Lippai M, Simon-Vecsei Z, Molnár M, Fürstenhoffer F, Juhász G, Lőrincz P.   +9 more
europepmc   +1 more source

Fluorophore Modulates Intracellular Distribution of Enzyme‐Instructed Self‐Assembly of Short Peptides in Osteosarcoma Cells

Small Methods, EarlyView.
Fluorophores at the peptide C‐terminus reprogram EISA behavior in osteosarcoma cellsshifting ER vs mitochondrial targeting, altering assembly, and tuning cytotoxicity. Abstract Enzyme‐instructed self‐assembly (EISA) of peptides offers a versatile strategy for developing intracellular nanomedicines, yet the role of C‐terminus fluorophores in modulating ...
Yali Huang, Meihui Yi, Yuchen Qiao, Bing Xu   +3 more
wiley   +1 more source

Mechanisms underlying centriole stability. [PDF]

J Biol Chem
Biven E, Wang JT.
europepmc   +1 more source

Integrated multi‐omics analysis reveals metabolic reprogramming as a key driver of angiotensin II‐induced vascular remodeling

VIEW, EarlyView.
This study investigates the molecular alterations underlying angiotensin II (Ang II)‐induced vascular remodeling in cardiovascular diseases using a multi‐omics approach. Through data exploration and integrated multi‐omics analysis, our findings reveal that Ang II‐driven vascular injury in vascular smooth muscle cells is mediated by metabolic ...
Yiwei Hu, Dan Zhao, Lingyan Zhong, Jianxujie Zheng, Dongxue Zhang, Enhui Wu, Qian Shi, Liang Qiao, Ling Lin   +8 more
wiley   +1 more source

The Mechanism of NLRP3 Inflammasome Activation and Its Roles in Chronic Rhinosinusitis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT NLRP3 (NLR family pyrin domain containing 3) is one of the crucial receptors in pathogen recognition receptor (PRR) families which can recognize the pathogen‐associated molecular patterns (PAMPs) and the damage‐associated molecular patterns (DAMPs), thus triggering innate immune response. After NLRP3 activation, it recruits the adaptor protein
Dong‐Lin Li, Yue Li, Yan‐Jie Jiang, Ge‐Hua Zhang, Li‐Hong Chang   +4 more
wiley   +1 more source

A dynamic barrier: remodeling of the nuclear envelope during closed mitosis in malaria parasites. [PDF]

mSphere
Absalon S.
europepmc   +1 more source

Identification of upregulated genes in pulmonary hypertension using RNA sequencing profiling. [PDF]

Bioinformation
J JB, R J, Murugan S, G SL.
europepmc   +1 more source

Microtubule polymerization generates microtentacles important in circulating tumor cell invasion. [PDF]

Biophys J
Kainka L, Shaebani R, Kaiser K, Bosche J, Santen L, Lautenschläger F.   +5 more
europepmc   +1 more source

Molecular Guardians of Oocyte Maturation: A Systematic Review on TUBB8, KIF11, and CKAP5 in IVF Outcomes. [PDF]

Int J Mol Sci
Voros C, Sapantzoglou I, Athanasiou D, Varthaliti A, Mavrogianni D, Bananis K, Athanasiou A, Athanasiou A, Papadimas G, Gkirgkinoudis A, Papapanagiotou I, Migklis K, Vaitsis D, Koulakmanidis AM, Mazis Kourakos D, Ivanidou S, Daskalaki MA, Theodora M, Antsaklis P, Loutradis D, Daskalakis G.   +20 more
europepmc   +1 more source