Results 21 to 30 of about 63,482 (321)

The centriolar satellite protein Cfap53 facilitates formation of the zygotic microtubule organizing center in the zebrafish embryo. [PDF]

Development, 2022
Willekers S, Tessadori F, van der Vaart B, Henning HH, Stucchi R, Altelaar M, Roelen BAJ, Akhmanova A, Bakkers J.   +8 more
europepmc   +2 more sources

NLRP7, a Nucleotide Oligomerization Domain-like Receptor Protein, Is Required for Normal Cytokine Secretion and Co-localizes with Golgi and the Microtubule-organizing Center [PDF]

Journal of Biological Chemistry, 2011
Background: NLRP7 is responsible for recurrent hydatidiform moles, but its functional role is unknown. Results: NLRP7 mutations impair IL-1β and TNF secretion but do not affect IL-1β processing.
Christiane Messaed, Elie Akoury, Ugljesa Djuric, Jibin Zeng, Maya Saleh, Lucy Gilbert, Muhieddine Seoud, Salman T. Qureshi, Rima Slim   +8 more
openalex   +2 more sources

Procedure for Bovine ICSI, not Sperm Freeze-drying, Impairs the Function of the Microtubule-organizing Center

Journal of reproduction and development, 2011
This study was designed to investigate whether freeze-dried (FD) bull spermatozoa maintained the function of the microtubule-organizing center (MTOC) after rehydration and intracytoplasmic sperm injection (ICSI).
Hiromasa Hara, Hany Abdalla, Hiroshi Morita, Masashige Kuwayama, Masumi Hirabayashi, Shinichi Hochi   +5 more
openalex   +3 more sources

The Reduction in Microtubule Arrays Caused by the Dysplasia of the Non-Centrosomal Microtubule-Organizing Center Leads to a Malformed Organ of Corti in the Cx26-Null Mouse. [PDF]

Biomedicines, 2022
Qiu Y, Xu K, Xie L, Chen S, Sun Y.
europepmc   +3 more sources

The impact of post-translational modifications and subcellular localization on NLRP3 inflammasome activation: A systematic review [PDF]

Cell Communication and Signaling
Background The NOD-like receptor pyrin domain-containing 3 (NLRP3) inflammasome is crucial for innate immunity. However, its uncontrolled and dysregulated activation may cause various inflammatory and autoimmune disorders.
Shuchi Zhang, Muhammad Usman, Qianxi Wu, Yingjie Gao, Lifeng Fu, Maoping Chu, Chang Jia   +6 more
doaj   +2 more sources

Cytoskeletal remodeling via CAMSAP3 downregulation drives resistance to osimertinib in NSCLC cells [PDF]

Cell Death and Disease
Osimertinib, also known as AZD9291, is a highly potent and selective EGFR mutants (including exon 19 deletion, L858R/T790M) inhibitor that significantly inhibits EGFR phosphorylation signaling. However, acquired resistance to osimertinib is inevitable in
Fei Yang, Zhen Wang, Xiao Han, Jinjin Zhong, Zhanwu Hou, Shuying Bian, Jiangang Long, Huadong Liu   +7 more
doaj   +2 more sources

Centrosomal and Non-Centrosomal Microtubule-Organizing Centers (MTOCs) in Drosophila melanogaster [PDF]

Cells, 2018
The centrosome is the best-understood microtubule-organizing center (MTOC) and is essential in particular cell types and at specific stages during Drosophila development.
Marisa M. L. Tillery, Caitlyn Blake-Hedges, Yiming Zheng, Rebecca A. Buchwalter, Timothy L. Megraw   +4 more
doaj   +3 more sources

Depletion of pericentrin in mouse oocytes disrupts microtubule organizing center function and meiotic spindle organization. [PDF]

Mol Reprod Dev, 2014
Ma W, Viveiros MM.
europepmc   +2 more sources

Gathering up meiotic telomeres: a novel function of the microtubule-organizing center. [PDF]

Cell Mol Life Sci, 2014
Yamamoto A.
europepmc   +2 more sources

Yeast ubiquitin-like genes are involved in duplication of the microtubule organizing center. [PDF]

Journal of Cell Biology, 1996
KAR1 is required for duplication of the Saccharomyces cerevisiae microtubule organizing center, the spindle pole body (SPB) (Rose, M.D., and G.R. Fink, 1987. Cell. 48:1047-1060). Suppressors of a kar1 allele defective for SPB duplication were isolated in
Sue Biggins, Irena L. Ivanovska, Mark D. Rose   +2 more
openalex   +2 more sources