Results 181 to 190 of about 199,967 (323)

Potential New Expression Biomarkers for Anorexia Nervosa

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Anorexia nervosa (AN) is a psychiatric disorder with an estimated heritability of around 70%. Although the largest meta‐analysis of genome‐wide association studies on AN identified independent risk‐conferring loci for the disorder, the molecular mechanisms underlying the genetic basis of AN remain to be elucidated.
Camille Verebi, Nicolas Lebrun, Justine Vily Petit, Odile Viltart, Philibert Duriez, Benjamin Saint‐Pierre, Philip Gorwood, Nicolas Ramoz, Thierry Bienvenu   +8 more
wiley   +1 more source

CEP162: A critical regulator of ciliary transition zone assembly and its implications in ciliopathies. [PDF]

J Cell Commun Signal
Yin J, Bai J, He X, He W, Miao H, Zhang M, Yu Z, Ni B.   +7 more
europepmc   +1 more source

Microtubules and protein secretion in rat lacrimal glands. Relationship between colchicine binding and its inhibitory effect on the intracellular transport of proteins.

, 1978
Anne‐Marie Chambaut‐Guérin, P. Müller, B. Rossignol   +2 more
openalex   +1 more source

BALD-2: a mutation affecting the formation of doublet and triplet sets of microtubules in Chlamydomonas reinhardtii. [PDF]

, 1975
Ursula Goodenough, H S StClair
openalex   +1 more source

Alzheimer's Association clinical practice guideline for the Diagnostic Evaluation, Testing, Counseling, and Disclosure of Suspected Alzheimer's Disease and Related Disorders (DETeCD‐ADRD): Executive summary of recommendations for primary care

Alzheimer's &Dementia, EarlyView.
Abstract US clinical practice guidelines for the diagnostic evaluation of cognitive impairment due to Alzheimer's disease (AD) or AD and related dementias (ADRD) are decades old and aimed at specialists. This evidence‐based guideline was developed to empower all—including primary care—clinicians to implement a structured approach for evaluating a ...
Alireza Atri, Bradford C. Dickerson, Carolyn Clevenger, Jason Karlawish, David Knopman, Pei‐Jung Lin, Mary Norman, Chiadi Onyike, Mary Sano, Susan Scanland, Maria Carrillo   +10 more
wiley   +1 more source

Kinetic regulation of kinesin's two motor domains coordinates its stepping along microtubules. [PDF]

Elife
Niitani Y, Matsuzaki K, Jonsson E, Vale RD, Tomishige M.   +4 more
europepmc   +1 more source

SYNTHESIS AND STORAGE OF MICROTUBULE PROTEINS BY SEA URCHIN EMBRYOS [PDF]

, 1971
Rudolf A. Raff, Gerald Greenhouse, Kenneth W. Gross, Paul R. Gross   +3 more
openalex   +1 more source

The tau isoform 1N4R confers vulnerability of MAPT knockout human iPSC‐derived neurons to amyloid beta and phosphorylated tau‐induced neuronal dysfunction

Alzheimer's &Dementia, EarlyView.
Abstract INTRODUCTION Human tau protein, composed of six brain‐specific isoforms, is a major driver of Alzheimer's disease (AD). The role of its isoforms however remains unclear and human AD models are scarce. METHODS We generated human MAPT– (tau–) knockout (KO) induced pluripotent stem cells (iPSC) using CRISPR/Cas9, differentiated these into ...
Sarah Buchholz, Mohamed Aghyad Al Kabbani, Michael Bell‐Simons, Lena Kluge, Cagla Cagmak, Jennifer Klimek, Natja Haag, Lukas C. Iohan, Audrey Coulon, Marcos R. Costa, Devrim Kilinc, Hans Zempel   +11 more
wiley   +1 more source

Redox signaling modulates axonal microtubule organization and induces a specific phosphorylation signature of microtubule-regulating proteins. [PDF]

Redox Biol
Conze C, Trushina NI, Monteiro-Abreu N, Singh L, Romero DV, Wienbeuker E, Schwarze AS, Holtmannspötter M, Bakota L, Brandt R.   +9 more
europepmc   +1 more source

Individual microtubules viewed by immunofluorescence and electron microscopy in the same PtK2 cell [PDF]

, 1978
Mary Osborn, R. M. Webster, K. Weber
openalex   +1 more source