Results 181 to 190 of about 406,325 (331)

Cancer Stem Cells Shift Metabolite Acetyl‐Coenzyme A to Abrogate the Differentiation of CD103+ T Cells

Advanced Science, EarlyView.
Lei et al. demonstrate that cancer stem cells (CSCs) play a pivotal role in impairing the differentiation of CD103+ T cells in patients with non‐small‐cell lung cancer. The key mechanism involves CSC‐derived acetyl‐CoA, which disrupts CD103+ T cell differentiation by sequentially inducing acetylation and ubiquitination of the Blimp‐1 protein. Targeting
Jiaxin Lei, Huiyan Ji, Jing Guo, Mengdi Liu, Danhua Su, Yiran Zheng, Lin Xu, Qinghua Cao, Tao Ren, Jun Gui, Zhenke Wen   +10 more
wiley   +1 more source

Microtubule dependent changes in cell polarity are required for mammary epithelial cell migration and branching morphogenesis. [PDF]

Biol Open
Fraser AK, Carreras J, Ryan IA, Zoll J, Ewald AJ.   +4 more
europepmc   +1 more source

2P039 Ectopic A-lattice seams destabilize microtubules(01B. Protein: Structure & Function,Poster,The 52nd Annual Meeting of the Biophysical Society of Japan(BSJ2014))

, 2014
Miho Katsuki, Douglas R. Drummond, Robert A. Cross   +2 more
openalex   +2 more sources

Coordinated Regulation of Hypocotyl Cell Elongation by Light and Ethylene through a Microtubule Destabilizing Protein [PDF]

, 2017
Qianqian Ma, Xiaohong Wang, Jingbo Sun, Tonglin Mao   +3 more
openalex   +1 more source

Connexin 26 Functions as a Direct Transcriptional Regulator During the Cochlea Development

Advanced Science, EarlyView.
Connexin26 can not only form intercellular channels that mediate rapid communication on the cell membrane, but also enter the nucleus as a transcription factor to directly regulate the transcription of nuclear genes. In the developing cochlea, Cx26 can control the maturation of the molecular scissor ADAM10 by regulating the transcription of TspanC8 ...
Xiaozhou Liu, Le Xie, Yuan Jin, Sen Chen, Xinyu Shi, Yanjun Zong, Zhengdong Zhao, Wei‐Jia Kong, Yu Sun   +8 more
wiley   +1 more source

1P040 Structure and function of katanin, a microtubule severing protein(01B. Protein : Structure & Function,Poster,The 52nd Annual Meeting of the Biophysical Society of Japan(BSJ2014))

, 2014
Naoko Iwaya, Syouta Noda, Natsuko Goda, Takeshi Tenno, Hidekazu Hiroaki   +4 more
openalex   +2 more sources

The biosynthetic gene cluster for the microtubule-stabilizing agents epothilones A and B from Sorangium cellulosum So ce90 [PDF]

, 2000
István Molnár, Thomas Schupp, M. ONO, RE Zirkle, M Milnamow, Brian Nowak-Thompson, N.K. Van Den Engel, Christiane Toupet, Ansgar Stratmann, DD Cyr, J Görlach, J. K. MAYO, Anren Hu, Stephen A. Goff, Jochen Schmid, JM Ligon   +15 more
openalex   +1 more source

ISOLATED MICROTUBULES [PDF]

The Journal of Cell Biology, 1965
openaire   +2 more sources

Evolutionary Divergence of an Ethylene‐Responsive Transcriptional Cascade Governs a Dose‐Dependent Balance between Cotton Fiber Length and Strength

Advanced Science, EarlyView.
A tunable, ethylene‐responsive cascade governing the dose‐dependent balance between fiber length and strength is unveiled. Elevated ethylene strengthens modern tetraploid cotton (G. hirsutum) fibers but elongates those of its diploid ancestor (G. arboreum). This phenotypic switch is traced to an evolutionary functional inversion of a conserved EIN3‐ERF‐
Jie Zhang, Mengli Yu, Yuling Guo, Jie Li, Gailing Gu, Ghulam Hussain, Shuya Ma, Fuguang Li, Hongwei Xue, Zhaoen Yang, Zuoren Yang   +10 more
wiley   +1 more source

MCAK recognizes the nucleotide-dependent feature at growing microtubule ends. [PDF]

Elife
Chen W, Song YL, He JF, Liang X.
europepmc   +1 more source