Results 171 to 180 of about 223,853 (265)

Systematic Identification of Molecular Signatures Dictating Therapeutic Effects of Clinically First-Line Chemotherapy Regimens for Human Gastric Cancer Patients Based on Organoid Model. [PDF]

MedComm (2020)
Yang J, Qi S, Gao Y, Lu J, Deng L, Wu X, Zhao Y, Liu Y, Ma Y, Song J, Xue L, Wen L, Fu W, Tang F, Zhou X.   +14 more
europepmc   +1 more source

Biochemical and Immunohistochemical Associations of TDP‐43 and Cryptic RNA With Hippocampal and Amygdala Volumetrics in Alzheimer's Disease

Annals of Neurology, EarlyView.
Objective Immunohistochemically (IHC) measured transactive response DNA‐binding protein 43 (TDP‐43) inclusions are observed in Alzheimer's disease (AD) and are associated with medial temporal lobe atrophy. Accumulation of cryptic exons occurs in AD in response to TDP‐43 pathology.
Hossam Youssef, Rodolfo G. Gatto, Nikhil B. Ghayal, Virginia Estades Ayuso, Karen R. Jansen‐West, Judith A. Dunmore, Yuping Song, Mei Yue, Casey N. Cook, Michael DeTure, Bailey D. Rawlinson, Monica Castanedes‐Casey, Clifford R. Jack Jr, Ronald C. Petersen, Dennis W. Dickson, Leonard Petrucelli, Jennifer L. Whitwell, Mercedes Prudencio, Keith A. Josephs   +18 more
wiley   +1 more source

Cytoskeletal Dynamics and Molecular Motor Dysfunction in Psychiatric Disorders: Insights from Schizophrenia and Autism Spectrum Disorder. [PDF]

Biology (Basel)
Nakamura K, Kubo A, Sanaka S, Kamiya S, Itagaki K, Sasaki T.   +5 more
europepmc   +1 more source

Dissecting cytoskeletal crosstalk through reconstituted actin-microtubule systems. [PDF]

Mol Biol Cell
Chowdhury MAH, Kandel R, Reinemann DN.
europepmc   +1 more source

Photocaged Oxytocin and Vasopressin Probes to Decipher Neuropeptide Signalling With High Spatiotemporal Resolution

Angewandte Chemie International Edition, EarlyView.
Novel and biocompatible photoactivatable oxytocin and vasopressin probes, utilising state‐of‐the‐art photocages, remain inactive in the dark. Light exposure facilitates rapid spatiotemporal receptor activation and phospholipase C (PLC)‐mediated downstream signalling. Figure created in https://BioRender.com.
Konstantin Raabe, Predrag Kalaba, Xuan Ling Hilary Yong, Greta Crudeli, Sarah Melzer, Erik Keimpema, Victor Anggono, Markus Muttenthaler   +7 more
wiley   +1 more source

Accessibility of the unstructured α-tubulin C-terminal tail is controlled by microtubule lattice conformation. [PDF]

Elife
Hotta T, Pimm ML, Thomas EC, Yue Y, DeLear P, Blasius L, Cianfrocco MA, DeSantis ME, Horiuchi R, Higaki T, Sept D, Ohi R, Verhey KJ.   +12 more
europepmc   +1 more source

Myonuclear Domain-Associated and Central Nucleation-Dependent Spatial Restriction of Dystrophin Protein Expression. [PDF]

J Cachexia Sarcopenia Muscle
Chwalenia K, Feng VY, Hemmer N, Hildyard JCW, Roskrow LE, Piercy RJ, Wang ET, Aartsma-Rus A, van Putten M, Wood MJA, Roberts TC.   +10 more
europepmc   +1 more source

Morphometric analysis of postnatal lung development in the gray short‐tailed opossum (Monodelphis domestica): An ultrastructural study

The Anatomical Record, EarlyView.
Abstract An ultrastructural morphometric analysis of the postnatal development of the lung in the gray short‐tailed opossum (Monodelphis domestica) has been conducted to evaluate the morphofunctional status of this poorly developed marsupial lung immediately following parturition.
Kirsten Ferner
wiley   +1 more source

Posttranslational encoding of microtubule provides unique recognition patterns for associated proteins

Janke C, Krishnan A, Desvigne-Hansch E, Henriot V, Khanfir S, Genova M, Magiera M, Grycova L, Dodokova A, Braun M, Lansky Z.   +10 more
europepmc   +1 more source

Microenvironmental stiffness directs microtubule perturbation in chondrocyte mitosis via ILK-refilinB/Smad3 axis. [PDF]

Bone Res
Duan M, Zhou C, Su G, Zhang C, Ren J, Chi Q, Liu X, Yang L, Bai H, Zeng YC, Kim S, Zhai Y, Oh CY, Ye AY, Chen Y, Si L, Liu X, Xie J.   +17 more
europepmc   +1 more source