Results 111 to 120 of about 242,523 (302)

CENTROSOMES AND MICROTUBULES DURING MEIOSIS IN THE MUSHROOM BOLETUS RUBINELLUS [PDF]

, 1971
David J. McLaughlin
openalex   +1 more source

Targeting Methylglyoxal Metabolism to Enhance Ferroptosis Sensitivity in Tumor Therapy

Advanced Science, EarlyView.
This study reveals how blocking a detox enzyme called GLO1 increases the buildup of a toxic molecule, methylglyoxal (MGO), which triggers cancer cell death by ferroptosis. A protein called PJA1 drives this process. Targeting the PJA1–GLO1 pathway boosts the effectiveness of ferroptosis‐inducing treatments in tumors, offering a promising approach for ...
Xinyue Zhang, Leng Han, Zimu Wang, Hanghui Yu, Jiao Liu, Rui Kang, Daolin Tang, Zhengjia Liu, Xianlong Du, Enyong Dai   +9 more
wiley   +1 more source

INTRANUCLEAR MICROTUBULE ORGANIZING CENTER IN EARLY PROPHASE NUCLEI OF THE PLASMODIUM OF THE SLIME MOLD, PHYSARUM POLYCEPHALUM [PDF]

, 1973
Kenji Tanaka
openalex   +1 more source

API5 Phosphorylation Promotes Antiviral Immunity by Inhibiting Degradation of Cytosolic RNA Sensor RLRs

Advanced Science, EarlyView.
Ubiquitin‐mediated selective autophagy plays a critical role in antiviral innate immunity. The study shows that upon RNA virus infection, cytoplasmic API5 undergoes SRPK1‐dependent phosphorylation at S464, which in turn suppresses p62 K141 ubiquitination‐dependent autophagy.
Tingjuan Deng, Jianan Xu, Linglong Qin, Xingbo Wang, Chenhe Lu, Yanming Huang, Da Liu, Yan Yan, Weiren Dong, Pinglong Xu, Jiyong Zhou   +10 more
wiley   +1 more source

THE “9 + 1” PATTERN OF MICROTUBULES IN SPERMATOZOA OF Mesostoma (PLATYHELMINTHES, TURBELLARIA)

, 1969
Catherine Henley, Donald P. Costello, Mary Beth Thomas, W. Donald Newton   +3 more
openalex   +1 more source

CROSS-BRIDGES ON THE MICROTUBULES OF COOLED INTERPHASE HELA CELLS [PDF]

, 1971
A.N. Bhisey, Jerome J. Freed
openalex   +1 more source

NADPH Oxidase Inhibition Promotes Brain Resilience by Attenuating Tauopathy and Neuroinflammation in Alzheimer's Disease

Advanced Science, EarlyView.
CRB‐2131, as a novel Nox inhibitor, suppresses brain oxidation, tauopathy, and neuro‐inflammation, thereby preventing death of mature neurons and promoting regeneration of immature neurons. Ultimately, this fosters a resilient brain and protects cognition.
Jihyeon Lee, Seunghwan Sim, Yinglan Jin, Hyejun Park, Eun Young Byeon, Su Jin Kim, Sujin Yun, Hye Eun Lee, Da Un Jeong, Jung Min Suh, In Hye Lee, Ho‐Young Lee, Yongseok Choi, Yun Soo Bae   +13 more
wiley   +1 more source

Fine Structure of the Epithelium of the Gut in the Crayfish (<i>Procambarus clarkii</i>) with Special Reference to the Cytoplasmic Microtubules

, 1968
Terumasa Komuro, Torao Yamamoto
openalex   +2 more sources

Intracisternal microtubules and flagellar hairs ofGonyostomum semen(Ehrenb.) Diesing [PDF]

, 1973
Peter Heywood
openalex   +1 more source

The Critical Role of Enhanced OXPHOS and Mitochondrial Hyperpolarization in Simulated Microgravity‐Induced Oocyte Maturation Arrest

Advanced Science, EarlyView.
Simulated microgravity induces distinct mitochondrial hyperactivation patterns‐elevated OXPHOS and MMP‐which accelerate meiosis without SAC failure but delays MTOC coalescence, leading to spindle defects and meiotic arrest. Prolonging M‐phase restores MTOC assembly and oocyte maturation.
Lei Ge, Yuqing Gao, Feifei Du, Chiyuan Ma, Tianxia Xiao, Yali Yang, Xiaohua Lei, Jian V. Zhang   +7 more
wiley   +1 more source