Results 141 to 150 of about 329,213 (392)

Picomolar Detection of Tau Protein Using 1D Photonic Crystal Biochips for Alzheimer's Disease Diagnosis

open access: yesAdvanced Sensor Research, EarlyView.
Elevated levels of Tau in cerebrospinal fluids or other body fluids are associated with the progression of Alzheimer's disease. An optical technique, based on a dual label‐free and fluorescence operation mode, is developed to detect Tau protein in both standard running buffer and cerebrospinal fluid.
Alberto Sinibaldi   +7 more
wiley   +1 more source

HURP facilitates spindle assembly by stabilizing microtubules and working synergistically with TPX2

open access: yesNature Communications
In vertebrate spindles, most microtubules are formed via branching microtubule nucleation, whereby microtubules nucleate along the side of pre-existing microtubules.
Venecia Alexandria Valdez   +4 more
doaj   +1 more source

Cloning and expression of a human kinesin heavy chain gene: interaction of the COOH-terminal domain with cytoplasmic microtubules in transfected CV-1 cells. [PDF]

open access: yes, 1992
To understand the interactions between the microtubule-based motor protein kinesin and intracellular components, we have expressed the kinesin heavy chain and its different domains in CV-1 monkey kidney epithelial cells and examined their distributions ...
Bernstein, HD   +6 more
core  

Optical Microfiber Biomedical Sensors: Classification, Applications, and Future Perspectives

open access: yesAdvanced Sensor Research, EarlyView.
This review delves deeply into the various types of optical microfiber biosensors, grounded firmly in their fundamental principles, and underscores their indispensable roles in pushing forward biomedical advancements. It examines the latest advancements, challenges faced by these biosensors in practical applications, future directions, breakthroughs ...
Lili Liang   +5 more
wiley   +1 more source

Microtubules Nonlinear Models Dynamics Investigations through the exp(−Φ(ξ))-Expansion Method Implementation

open access: yesMathematics, 2016
In this research article, we present exact solutions with parameters for two nonlinear model partial differential equations(PDEs) describing microtubules, by implementing the exp(−Φ(ξ))-Expansion Method ...
Nur Alam, Fethi Bin Muhammad Belgacem
doaj   +1 more source

Microtubules, signalling and abiotic stress.

open access: yesThe Plant Journal, 2013
Plant microtubules, in addition to their role in cell division and axial cell expansion, convey a sensory function that is relevant for the perception of mechanical membrane stress and its derivatives, such as osmotic or cold stress.
P. Nick
semanticscholar   +1 more source

Bacterial‐Based Molecular Communication: Simulation of a Fixed and Receding Receiver Scenarios in Varied Viscosities and Environmental Conditions

open access: yesAdvanced Theory and Simulations, EarlyView.
This study presents a robust 3D simulation for BBMC, focusing on both fixed and receding receiver scenarios across various conditions. Key parameters such as D, Q, u, and d are tested at different values to assess the performance and reliability of BBMC in applications like drug delivery, addressing critical challenges in nanoscale communication with ...
Mustafa Ozan Duman   +3 more
wiley   +1 more source

Further expansion and confirmation of phenotype in rare loss of YWHAE gene distinct from Miller–Dieker syndrome

open access: yesAmerican Journal of Medical Genetics Part A, Volume 191, Issue 2, Page 526-539, February 2023., 2023
Abstract Deletion of 17p13.3 has varying degrees of severity on brain development based on precise location and size of the deletion. The most severe phenotype is Miller–Dieker syndrome (MDS) which is characterized by lissencephaly, dysmorphic facial features, growth failure, developmental disability, and often early death.
Elizabeth K. Baker   +9 more
wiley   +1 more source

MAP7 regulates axon morphogenesis by recruiting kinesin-1 to microtubules and modulating organelle transport. [PDF]

open access: yes, 2018
Neuronal cell morphogenesis depends on proper regulation of microtubule-based transport, but the underlying mechanisms are not well understood.
Ma, Le   +3 more
core   +1 more source

Bilirubin Targeting WNK1 to Alleviate NLRP3‐Mediated Neuroinflammation

open access: yesAdvanced Science, EarlyView.
At physiological concentrations, bilirubin binds to the kinase domain of WNK1, thereby augmenting its activity and facilitating the phosphorylation of downstream SPAK/OSR1. This phosphorylation inhibits KCC2 activity, leading to elevate intracellular chloride levels in neurons.
Linfei Mao   +14 more
wiley   +1 more source

Home - About - Disclaimer - Privacy