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Current Opinion in Cell Biology, 2003
Microtubule nucleation is the process in which several tubulin molecules interact to form a microtubule seed. Microtubule nucleation occurs spontaneously in purified tubulin solutions, and molecular intermediates between tubulin dimers and microtubules have been identified.
Didier, Job +2 more
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Microtubule nucleation is the process in which several tubulin molecules interact to form a microtubule seed. Microtubule nucleation occurs spontaneously in purified tubulin solutions, and molecular intermediates between tubulin dimers and microtubules have been identified.
Didier, Job +2 more
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τ Regulation of Microtubule‐Microtubule Spacing and Bundling
Journal of Neurochemistry, 1994Abstract: τ proteins are microtubule‐associated proteins that promote microtubule polymerization in vitro and in vivo. They are a family of neuronal proteins with apparent molecular weights in the range 50,000–68,000 determined by sodium dodecyl sulfate‐polyacrylamide gel electrophoresis. Recently, a new member of this family has been described and its
Irene S. Georgieff +3 more
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1984
The mitotic chromosome movements are discussed in relation with recent studies on tubulins, their assembly and disassembly, and the associated proteins. The role of contractile proteins in the mitotic spindle is considered, and also that of the calcium regulating protein (CDR) which has been demonstrated recently in the mitotic spindle.
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The mitotic chromosome movements are discussed in relation with recent studies on tubulins, their assembly and disassembly, and the associated proteins. The role of contractile proteins in the mitotic spindle is considered, and also that of the calcium regulating protein (CDR) which has been demonstrated recently in the mitotic spindle.
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BioEssays, 1997
AbstractHow do cells order their cytoplasm? While microtubule organizing centers have long been considered essential to conferring order by virtue of their microtubule nucleating activity, attention has currently refocused on the role that microtubule motors play in organizing microtubules.
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AbstractHow do cells order their cytoplasm? While microtubule organizing centers have long been considered essential to conferring order by virtue of their microtubule nucleating activity, attention has currently refocused on the role that microtubule motors play in organizing microtubules.
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Implications of Microtubule Polarity for Microtubule Function
1986Microtubules (MTs) and actin filaments have an intrinsic molecular polarity based on the unipolar stacking of their asymmetrical subunits. Filament polarity is believed to be important for many cellular activities. For example, the interaction of actin and myosin that produces shortening of the sarcomere in striated muscle depends on the correct ...
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