Results 81 to 90 of about 331,243 (309)

Optical Coherence Tomography Angiography (OCTA) in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorder

Frontiers in Neurology, 2020
Vascular changes are increasingly recognized as important factors in the pathophysiology of neuroinflammatory disease, especially in multiple sclerosis (MS).
Iris Kleerekooper, Iris Kleerekooper, Sarah Houston, Adam M. Dubis, S. Anand Trip, Axel Petzold, Axel Petzold, Axel Petzold   +7 more
doaj   +1 more source

Microvascular abnormalities in dry eye patients

, 2018
This study was conducted to evaluate conjunctival blood flow velocities and microvascular network density in patients with dry eye disease (DED). Twenty-five patients with DED and 25 healthy controls were recruited.
Chen, Wan, Wang, Bowen, Li, Saiqun, Deng, Yuqing, Saiqun Li, Yuan, Jin, Peng, Lulu, Hong Jiang, Bowen Wang, Yang, Ruhui, Zhang, Henan, Wan Chen, Ruhui Yang, Li, Meng, Jianhua Wang, Zhong, Jing, Lulu Peng, Henan Zhang, Yuqing Deng, Meng Li, Wang, Jianhua, Jing Zhong, Jin Yuan, Jiang, Hong   +23 more
core   +1 more source

Inhibition of VEGF‐Induced Angiogenesis and Vascular Leakage by Bicistronic Co‐Expression of Aflibercept and COMP‐Ang1

Advanced Healthcare Materials, EarlyView.
A bicistronic rAAV8 vector encoding Aflibercept (Afb) and COMP‐cAng1 simultaneously coordinates VEGF clearance and Tie2‐mediated vessel maturation. In a 3D angiogenesis‐on‐a‐chip model, rAAV8‐Afb/cAng1 effectively reverses pathological barrier breakdown under clinical disease‐mimicking challenges.
Bong‐Kyu Kim, Jaehong Min, Sang‐Hee Park, Subeen Shin, Sangbin Yu, Jeong‐Eun Park, Sujin Kim, Wooju Park, Jihoon Ko, Sunjong Kwon   +9 more
wiley   +1 more source

Combining CEUS and ultrasound parameters in thyroid nodule and cancer diagnosis: a TIRADS-based evaluation

Frontiers in Endocrinology
Contrast-enhanced ultrasonography (CEUS) has been established as a diagnostic tool for assessing microvascularization, essential for understanding angiogenesis in neoplastic development.
Andreea Borlea, Andreea Borlea, Luciana Moisa-Luca, Luciana Moisa-Luca, Alina Popescu, Felix Bende, Dana Stoian, Dana Stoian   +7 more
doaj   +1 more source

Mitochondria‐Targeted Nanotherapies in Aging Neurodegenerative Disorders: Emerging Prospects and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave, Ashish B. Jadhav, Nitin B. Waghamode, Shubham Khot, Rajiya Khan, Ravi Hole, Shankar M. Dhobale, Manoj Aswar, Keshav Raj Paudel   +8 more
wiley   +1 more source

Reconstruction of segmental mandibular defects: Current procedures and perspectives

Laryngoscope Investigative Otolaryngology, 2019
Background The reconstruction of segmental mandibular defects remains a challenge for the reconstructive surgeon, from both a functional and an esthetic point of view.
Arnaud Paré, Adeline Bossard, Boris Laure, Pierre Weiss, Olivier Gauthier, Pierre Corre   +5 more
doaj   +1 more source

Nailfold microvascular changes in patients with systemic lupus erythematosus and their associative factors

, 2019
ObjectivesThe aim of this study was to determine capillaroscopic changes in patients with systemic lupus erythematosus (SLE) and their predictors.MethodsFifty-nine SLE patients and 31 controls were enrolled in a cross-sectional study.
Etehadtavakol, Mahnaz,, Karbalaie, Abdolamir,, Fatemi, Alimohammad,, Erlandsson, Björn-Erik,, Emrani, Zahra,, Smiley, Abbas,   +5 more
core   +1 more source

Spatially Controlled Embedded Bioprinting of Prevascularized Spheroids‐Containing Biopatch Enables Functional Skin Regeneration

Advanced Healthcare Materials, EarlyView.
A spatially controlled embedded bioprinting strategy enables precise engineering of prevascularized multicellular spheroids within skin‐derived dECM bioinks. Optimized spheroid size, composition, and spacing promote vascular maturation, paracrine signaling, and tissue integration, resulting in enhanced angiogenesis, blood perfusion, and functional skin
Minjun Ahn, Gyu Tae Park, Dongjun Lee, Sik Yoon, Sae‐Ock Oh, Jae Ho Kim, Byoung Soo Kim   +6 more
wiley   +1 more source

Direct ink writing of microvascular networks [PDF]

, 2010
Nature is replete with examples of embedded microvascular systems that enable efficient fluid flow and distribution for autonomic healing, cooling, and energy harvesting.
Wu, Willie
core  

Making the Case for Organ‐on‐Chip Platforms in Long‐Acting Therapeutics Development

Advanced Healthcare Materials, EarlyView.
LATs release drug from a tissue‐resident depot over weeks to months, improving adherence, but their development is hampered by preclinical models that cannot reproduce the coupled tissue processes, sustained release, local microenvironment change, interstitial transport, immune and foreign‐body responses, and clearance that govern depot performance in ...
Charlie Gowans, Abdulwahhab Khedr, Panagiotis G. Georgiou, Nehir Arik, Ozlem Sen, Steve P. Rannard, Tom O. McDonald, Christos Tapeinos   +7 more
wiley   +1 more source