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Microvascular dysfunction: cause of diabetes and diabetes-related complications
, 2020 openaire +2 more sources
Coronary microvascular dysfunction in diabetes mellitus
Journal of International Medical Research, 2017 The significance, mechanisms and consequences of coronary microvascular dysfunction associated with diabetes mellitus are topics into which we have insufficient insight at this time.
Aleksandar Kibel +2 more
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Coronary Microvascular Dysfunction
New England Journal of Medicine, 2007The link between myocardial ischemia and obstructive atherosclerosis is established beyond any doubt and coronary angiography has demonstrated a relationship between the severity and extent of coronary artery disease (CAD) and survival. In the past two decades, however, a number of clinical studies have highlighted the potential role of coronary ...
CAMICI , PAOLO, Crea F.
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Microvascular Dysfunction in Sepsis
Microcirculation, 2000ABSTRACTThe microvascular dysfunction which occurs in sepsis involves all three elements of the microcirculation: arterioles, capillaries, and venules. In sepsis, the arterioles are hyporesponsive to vasoconstrictors and vasodilators. Sepsis also reduces the number of perfused capillaries, thereby impacting on oxygen diffusion to mitochondria.
C W, Lush, P R, Kvietys
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Advances in Coronary Microvascular Dysfunction
Heart, Lung and Circulation, 2009Considerable focus has been directed towards coronary arterial disease in the management of coronary heart disease, however the coronary microcirculation plays a major role in the regulation of coronary blood flow. Thus while we have multiple medical and revascularisation therapies to treat large vessel coronary artery disease, therapies directed ...
Beltrame, J., Crea, F., Camici, P.
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Coronary microembolization and microvascular dysfunction
International Journal of Cardiology, 2018Plaque erosion, fissuring or rupture occurs spontaneously or during coronary interventions. At some residual blood flow, the atherothrombotic debris is washed into the coronary microcirculation, causing physical obstruction, vasoconstriction, inflammation and ultimately microinfarction.
Heusch, Gerd +2 more
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Pathophysiology of coronary microvascular dysfunction
Vascular Pharmacology, 2023The term "coronary microvascular dysfunction" (CMD) encompasses several pathogenetic mechanisms resulting in functional and/or structural changes in the coronary microcirculation. CMD often determines angina and myocardial ischemia in a broad spectrum of cardiovascular diseases, including patients with ischemia with non-obstructive coronary arteries or
Filippo, Crea, Rocco A, Montone
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Coronary Microvascular Dysfunction, Microvascular Angina, and Treatment Strategies
JACC: Cardiovascular Imaging, 2015 Angina without coronary artery disease (CAD) has substantial morbidity and is present in 10% to 30% of patients undergoing angiography. Coronary microvascular dysfunction (CMD) is present in 50% to 65% of these patients. The optimal treatment of this cohort is undefined.
Mark A Marinescu, Jamieson M Bourque
exaly +3 more sources
Retinal microvascular dysfunction in hypercholesterolemia
Journal of Clinical Lipidology, 2018Hypercholesterolemia is one of the most important contributors to atherosclerosis. Whether hypercholesterolemia also affects the retinal microcirculation is unclear.The goal of our study was to assess the association of cholesterol levels with retinal microvascular function using dynamic and static retinal vessel analysis (RVA) in a primary prevention ...
Nägele, Matthias P +7 more
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