Endothelial Hydrogels Improve Microvascular Regeneration and Perfusion in Tracheal Scaffolds
Insufficient vascularization remains a major barrier to successful tracheal transplantation. This study demonstrates that an endothelial hydrogel significantly enhances graft perfusion and neovessel organization compared to non‐endothelial hydrogel controls.
Molly O. Hunter +6 more
wiley +1 more source
Substrate stiffness and shear stress collectively regulate the inflammatory phenotype in cultured human brain microvascular endothelial cells. [PDF]
Yates AK +8 more
europepmc +1 more source
Pinitol Improves Lipopolysaccharide-Induced Cellular Damage in Human Dermal Microvascular Endothelial Cells. [PDF]
Go MY, Kim J, Jeon CY, Kim M, Shin DW.
europepmc +1 more source
We employ freeform printing of thermo‐responsive poly(2‐oxazoline) to directly fabricate suspended sacrificial vascular templates within Organ‐on‐a‐chip devices. This enables circular, perfusable channels down to 200 µm without post‐processing.
Giulia Maria Di Gravina +7 more
wiley +1 more source
p23 protects against ferroptosis of brain microvascular endothelial cells in ischemic stroke. [PDF]
Zhao Y, Xu Y, Xu Q, He N, Zhao J, Liu Y.
europepmc +1 more source
Diabetic Peripheral Neuropathy: Molecular Staging, Risk Factors, Therapeutics, and Emerging Trends
The heterogeneous landscape of DPN can be unified through a tripartite pathogenic model encompassing progressive stages of metabolic dysregulation, chronic inflammation, and overt neuronal damage. Within this framework, six clinical subtypes were identified, namely, hyperglycemia‐driven, dyslipidemia‐driven, inflammation‐driven, dysvascularity‐driven ...
Xiaofeng Dai, Mingze Tang
wiley +1 more source
Polystyrene microplastics impair the function of human retinal microvascular endothelial cells and pericytes and increase vascular permeability <i>in vitro</i>. [PDF]
Yun JH.
europepmc +1 more source
Inflammation, Immunity, and Cardiovascular Diseases
Cardiovascular stress signals (e.g., hemodynamic shear, oxidized lipids, and ischemia) act on endothelial and immune cells to activate and amplify inflammation through NF‐κB, the NLRP3 inflammasome, and JAK/STAT signaling, inducing proinflammatory cytokines/chemokines (IL‐6, IL‐1β, TNF‐α, and CCL2) and self‐amplifying circuits; clinically, inflammatory
Dezhi Guo +8 more
wiley +1 more source
Transcriptome sequencing showed the differential expression of circRNAs in human pulmonary microvascular endothelial cells in acute respiratory distress syndrome. [PDF]
Wang N +7 more
europepmc +1 more source

