Results 271 to 280 of about 203,456 (311)

Microvascular Endothelial Cells from Heart

1990
Endothelial cells from macrovascular and microvascular vessels differ in many of their physiological properties [20, 21, 36, 55, 72]. For a detailed analysis of the metabolism and the physiological function of the microvascular endothelium, cultures of microvascular cells are required.
H. M. Piper, R. Spahr, S. Mertens, A. Krützfeldt, H. Watanabe   +4 more
openaire   +1 more source

Microvascular Endothelial Cells from Brain

1990
In addition to providing a nonthrombogenic surface, synthesizing factor VIII, and participating in vascular tone regulation, most endothelial cells of the vasculature of the brain participate in the blood-brain barrier. The bloodbrain barrier severely restricts the entry of macromolecules into nervous tissue and provides a selective permeability ...
P. D. Bowman, M. du Bois, K. Dorovini-Zis, R. R. Shivers   +3 more
openaire   +1 more source

Isolation and Culture of Microvascular Endothelial Cells

2003
The cultivation of endothelial cells from large vessels, predominantly from human umbilical veins (1,2), has become a routine procedure in many laboratories and has contributed to the development of modern vascular biology. However, there is convincing evidence that microvascular endothelial cells display a number of important functional differences ...
L, Richard, P, Velasco, M, Detmar
openaire   +2 more sources

VEGF differentially activates STAT3 in microvascular endothelial cells

The FASEB Journal, 2003
ABSTRACT Increased VEGF expression is found in several pathologies characterized by abnormal angiogenesis. Previous studies have shown that the transcription factor STAT3 mediates VEGF gene transcription and its activation. In this study, Western analysis and confocal immunocytochemistry were used to examine STAT3 activation in ...
Manuela, Bartoli, Dan, Platt, Tahira, Lemtalsi, Xiaolin, Gu, Steven E, Brooks, Mario B, Marrero, Ruth B, Caldwell   +6 more
openaire   +2 more sources

Dexamethasone effects on microvascular endothelial cell lipid composition

American Journal of Physiology-Cell Physiology, 1989
Previous studies have shown that treatment of cultured rabbit coronary microvessel endothelial (RCME) cells with dexamethasone results in a dose-, time-, and glucocorticoid-dependent inhibition of prostaglandin release. In the present study, the effects of dexamethasone on RCME membrane lipid composition and release of arachidonic acid were examined ...
M S, Medow, L, Intrieri, T, Moatter, M E, Gerritsen   +3 more
openaire   +2 more sources

Uptake of suramin by human microvascular endothelial cells

Cancer Letters, 1998
We have demonstrated for the first time that suramin is taken up by human dermal microvascular endothelial (HMEC-1) cells by an active process involving the caveolae system. The uptake of suramin was time-dependent and reduced by more than 90% when incubated in the presence of albumin or at 4 degrees C.
A R, Gagliardi, M F, Taylor, D C, Collins   +2 more
openaire   +2 more sources

Metabolism of anandamide in cerebral microvascular endothelial cells

Prostaglandins & Other Lipid Mediators, 2004
Anandamide (N-arachidonoylethanolamine, AEA), an endogenous cannabinoid receptor agonist, causes potent vasodilation in the cerebral circulation through an endothelial-dependent or -independent mechanism. We have investigated the processing of [3H]AEA in cultured mouse cerebral microvascular endothelial cells (MEC) in order to better understand its ...
Ping, Chen, Shanming, Hu, Shawn D, Harmon, Steven A, Moore, Arthur A, Spector, Xiang, Fang   +5 more
openaire   +2 more sources

Bovine microvascular endothelial cells immortalized with human telomerase

Journal of Cellular Biochemistry, 2006
AbstractPrimary cultures of bovine microvascular endothelial cells (BME) isolated from the adrenal cortex, are commonly used to study vascular endothelium, but have a limited life span. To circumvent these limitations, we have immortalized BME cells with either simian virus 40 (SV40) or with a retrovirus containing the coding region of human telomerase
Buser Llinares, Raphaële, Montesano, Roberto, Garcia, Irène, Dupraz, Philippe, Pepper, Michael Sean   +4 more
openaire   +3 more sources

FVIII production by human lung microvascular endothelial cells

Blood, 2006
While extrahepatic factor VIII (FVIII) synthesis suffices for hemostasis, the extrahepatic production sites are not well defined. We therefore investigated the ability of the human lungs to produce FVIII. Lungs from heart-beating donors who were declined for transplantation were perfused and ventilated in an isolated reperfusion model for 2 hours.
Marc, Jacquemin, Arne, Neyrinck, Maria Iris, Hermanns, Renaud, Lavend'homme, Filip, Rega, Jean-Marie, Saint-Remy, Kathelijne, Peerlinck, Dirk, Van Raemdonck, Charles James, Kirkpatrick   +8 more
openaire   +2 more sources

Erythromycin-induced CXCR4 expression on microvascular endothelial cells

American Journal of Physiology-Lung Cellular and Molecular Physiology, 2009
Although stromal-derived factor-1 (SDF-1) via its cognate receptor CXCR4 is assumed to play a critical role in migration of endothelial cells during new vessel formation after tissue injury, CXCR4 expression on endothelial cells is strictly regulated. Erythromycin (EM), a 14-membered ring macrolide, has an anti-inflammatory effect that may account for ...
Yasuyuki, Takagi, Naozumi, Hashimoto, Sem H, Phan, Kazuyoshi, Imaizumi, Masaki, Matsuo, Harunori, Nakashima, Izumi, Hashimoto, Yuta, Hayashi, Tsutomu, Kawabe, Kaoru, Shimokata, Yoshinori, Hasegawa   +10 more
openaire   +2 more sources