Results 261 to 270 of about 63,152 (354)
Lymph Node‐Targeted Nanomaterials for Controlled Nano‐Immunotherapy
This study primarily investigates lymph node‐targeted immunotherapeutic strategies, focusing on the mechanisms of immune response regulation within lymph nodes. By targeting distinct immune signaling pathways, we systematically explore the development of nanodrug delivery systems specifically designed for lymph node targeting to achieve enhanced ...
Yitong Zhao +4 more
wiley +1 more source
Large extracellular vesicles (microvesicles) in diabetic nephropathy: a systematic review of preclinical studies. [PDF]
Ghanem SK +3 more
europepmc +1 more source
The fat‐heart entanglement and the role of ‘osteopontin mechanics’ in cardiometabolic senescence
Abstract Background Residual cardiovascular (CV) risk persists despite therapeutic advances. Obesity is heterogeneous, and visceral adipose tissue (VAT) dysfunction (‘adiposopathy’) complicates risk stratification. Osteopontin (OPN) is a pleiotropic mediator implicated in VAT inflammation, senescence‐associated pathways, atherosclerosis and myocardial ...
Cristina Michelauz +3 more
wiley +1 more source
The glioblastoma virome across tumor and extracellular compartments. [PDF]
Ghorbani M +4 more
europepmc +1 more source
Intracellular communication controls the processing of generated signals so that every cell type can successfully respond. The extracellular matrix (ECM) is a fundamental regulator of cell communication and signaling through the strict orchestration and functions of its bioactive components.
Zoi Piperigkou +6 more
wiley +1 more source
Molecular Mechanisms of Extracellular Vesicle Biogenesis and Their Impact on the Design of Custom EVs. [PDF]
Carvalho Ferraz L +2 more
europepmc +1 more source
In this review, we summarise the major recent advances in Testicular Sex Cord‐Stromal Tumours, focusing on molecular alterations and biomarkers relevant for diagnosis, classification and prognosis. Testicular sex cord‐stromal tumours (TSCSTs) represent ~4%–8% of all testicular neoplasms.
João Lobo, Andres M Acosta
wiley +1 more source
Advances in the role of extracellular vesicles in circulating microRNA biomarker discovery for lung cancer. [PDF]
Belkozhayev A +8 more
europepmc +1 more source
Expanding the Immunologic and Neuronal Landscape of IgE‐Mediated Anaphylaxis
ABSTRACT Anaphylaxis is a life‐threatening immunoglobulin E (IgE)‐mediated type I hypersensitivity reaction with rising prevalence and burden. It involves mast cell degranulation upon cross‐linking of antigen on mast cell‐bound IgE. Mechanisms of IgE‐mediated anaphylaxis remain incompletely understood, particularly the induction of systemic symptoms ...
Ruchi Biswas +2 more
wiley +1 more source

