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Microvesicles and pre-eclampsia
Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health, 2013The maternal syndrome of pre-eclampsia is characterised by an excessive inflammatory response associated with endothelial dysfunction, brought about by the release of multiple factors from the placenta into the maternal circulation. While some of these factors are released as soluble molecules it is now apparent that many of them are associated with ...
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Microvesicles in Health and Disease
Archivum Immunologiae et Therapiae Experimentalis, 2012Microvesicles (or MVs) are plasma membrane-derived vesicles released from most eukaryotic cells constitutively during early apoptosis or at higher levels after chemical or physical stress conditions. This review looks at some of the functions of MVs in terms of intercellular communication and ensuant signal transduction, including the transport of ...
Jameel M, Inal +6 more
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Salivary microvesicles clot blood
Blood, 2011The capacity of saliva to clot blood has been documented in the scriptures (Luke 16:21), folklore, and in the medical literature of the 1920s when Hunter described the ability of saliva to clot blood and proposed it as a means to attenuate bleeding from gastric ulcers.1 In 1938, Glazko and Greenberg reported that saliva contains a cell-derived, protein-
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Blood/plasma secretome and microvesicles
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2013A major but hitherto overseen component of the blood/plasma secretome is that of extracellular vesicles (EVs) which are shed from all blood cell types. These EVs are made up of microvesicles (MVs) and exosomes. MVs, 100nm-1μm in diameter, are released from the cell surface, and are a rich source of non-conventionally secreted proteins lacking a ...
Jameel M, Inal +5 more
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Cell microvesicles during experimental endotoxemia
Bulletin of Experimental Biology and Medicine, 2006The dynamics of microvesicle formation in arterial blood in generalized Schwartzman phenomenon was studied. Successive (with 24-h interval) intravenous injections of endotoxin to rabbits in a dose of 1 mg/kg and 3 mg/kg caused an increase in the content of microvesicles in the blood, some of them containing ecto-5'-nucleotidase.
L D, Zubairova +4 more
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Antithrombin Activity of Erythrocyte Microvesicles
Bulletin of Experimental Biology and Medicine, 2017Coagulation and optical (based on chromogenic substrate) methods were employed to examine antithrombin activity of erythrocytes and erythrocyte-derived microvesicles isolated days 7, 14, 21, and 28 on erythrocyte storage. The erythrocyte-derived microvesicles decelerated fibrin clot formation from fibrinogen in the presence of exogenous thrombin both ...
G Ya, Levin, E G, Sukhareva
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Cell-derived microvesicles and cancer.
The Netherlands journal of medicine, 2009Blood and other body f luids contain cell-derived microvesicles. The presence of microvesicles in cancer patients was already noticed in the late 1970s. Since then, the prothrombotic state in cancer patients has invariably been associated with the presence of such microvesicles.
van Doormaal FF +4 more
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Microvesicles in developing synapses
Bulletin of Experimental Biology and Medicine, 1991The sensomotor cortex and nucleus caudatus of the embryonal (14-22 days) and newborn rats have been investigated by electron microscopic method. There were described two groups of microvesicles (10-20 nm in diameter) with smooth and rough external surface. They differ from other vesicular components of the developing synapses (such as synaptic vesicles,
L. E. Frumkina +2 more
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