Results 111 to 120 of about 29,720 (220)

Angiogenesis in Bladder Cancer: Relationship Between Microvessel Density and Tumor Prognosis

, 1995
Background: Tumor stage, histologic grade, and regional lymph node status are currently used to obtain prognostic information about bladder cancers. However, additional prognostic indicators are needed to aid clinicians in selecting patients who would ...
Nichols, Peter W, Cote, Richard J, Weidner, Noel, Skinner, Donald G, Bochner, Bernard H, Chen, Su-Chiu, Groshen, Susan   +6 more
core   +1 more source

Renal‐vascular axis: unmasking its role in vascular endothelial growth factor‐inhibitor vascular toxicity in cancer patients

British Journal of Pharmacology, EarlyView.
Abstract Vascular toxicity is a growing concern in cancer patients receiving vascular endothelial growth factor inhibitor (VEGFi) therapy, posing a significant threat to patient prognosis. While the primary mechanism of VEGFi‐induced vascular toxicity is linked to redox‐sensitive reactions that disrupt vascular tone, leading to hypertension and ...
Grace Whelan, Karla B. Neves
wiley   +1 more source

Utility of CD34 in Assessing Microvessel Density and Its Correlation With Clinicopathological Parameters in Colorectal Carcinoma Patients. [PDF]

Cureus, 2023
Pandey S, Shukla S, Vagha S.
europepmc   +1 more source

Relation between serum anti-p53 antibodies and microvessel density in bladder cancer patients

, 2004
Introduction: Etiology of serum anti-p53 antibodies in bladder cancer patients is still unknown. In this study we evaluated the relationship between serum anti-p53 antibodies and microvessel density in bladder cancer patients.
Miroglu, C, Gumus, E, Erdamar, S, Horasanli, K, Demirel, G, Ozmen, G   +5 more
core   +1 more source

Polarized effects of adenosine on blood–brain barrier integrity: Tightening from the luminal and opening from the abluminal side

British Journal of Pharmacology, EarlyView.
Background and Purpose Adenosine as a signalling molecule modifies blood–brain barrier (BBB) tightness in pathological conditions. Our aim was to investigate the direct and polarized effects of adenosine on the BBB using co‐culture and in vivo models. Experimental Approach The expression of adenosine receptors was measured by qRT‐PCR.
András Harazin, Gabriela Hurtado‐Alvarado, Lilla Barna, Arturo Contis‐Montes de Oca, Rocío Ruíz‐Manzano, Krisztián Laczi, András Kincses, Gergő Porkoláb, Gang Chen, Beatriz Gómez‐González, Mária A. Deli   +10 more
wiley   +1 more source

VEGF Exression and Microvessel Density in Oral Squamous Cell Carcinomas

, 2000
Angiogenesis is an essential process in tumor growth and metastasis. VEGF has been considered a leading candidate inducing tumor angiogenesis. VEGF expression was significantly correlated with clinical stage, lymph node matastasis, and prognosis of ...
홍성두, 홍삼표, 이재일, 임지준, 임창윤   +4 more
core  

Microvessel density relation to HIF1α expression and local disease relapse in operated and irradiated patients.

, 2013
Microvessel density relation to HIF1α expression and local disease relapse in operated and irradiated patients.
Marcos Brasilino de Carvalho (296248), Adriana Madeira Álvares da Silva (296268), Marcelo dos Santos (296251), Ana Maria da Cunha Mercante (296252), Iúri Drumond Louro (296265), Antônio José Gonçalves (307316), Eloiza Helena Tajara da Silva (307317)   +6 more
core   +1 more source

Gβγ subunit activation of KV7 and BKCa channels underlies calcitonin gene‐related peptide vasorelaxation in myogenic rat coronary resistance arteries

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose CGRP is a potent, clinically relevant coronary vasodilator known to play a role in cardioprotection. Here, we investigated the precise intracellular signalling pathways leading to vasodilation in small coronary arteries.
Lucy A. Donovan, JinHeng Lin, Milind Khashu, Christopher J. Garland, Kim A. Dora   +4 more
wiley   +1 more source

Lymph node reactivity and microvessel density in neck metastases of unknown primary squamous cell carcinoma

, 2006
BACKGROUND: neoangiogenesis and the immune response are important mechanisms in metastasis development. AIM: to evaluate lymph node reactivity and microvessel density in neck metastasis of occult primary squamous cell carcinoma considering their ...
Giovanini,Allan Fernando, Cervantes,Onivaldo, Amar, Ali [UNIFESP], Giovanini, Allan Fernando, Rosas, Marilene Paladino, Amar,Ali, Cervantes, Onivaldo, Amar, Ali, Rosas,Marilene Paladino, Cervantes, Onivaldo [UNIFESP]   +9 more
core   +1 more source

The nitty‐gritty of vascular permeability in cancer: targeting blood endothelium to control metastases

British Journal of Pharmacology, EarlyView.
Blood vascular permeability is a hallmark of cancer and acts as an active driver of metastatic dissemination. Metastasis accounts for the vast majority of cancer deaths, yet most work has focussed on tumour‐intrinsic traits and angiogenesis, while the specific contribution of endothelial barrier regulation to intravasation and extravasation remains ...
Pierre Boucher, Mérone Da Costa Oliveira, Adrien Levesque, Alexandre Rutault, Patrick Savoyaud, Nicolas Bréchot, Stéphane Germain   +6 more
wiley   +1 more source