Results 101 to 110 of about 51,554 (307)

Gut–Brain Axis Modulation by Short‐Chain Fatty Acids Exerts Disease‐Modifying Effects in a Murine Model of Drug‐Resistant Epilepsy

Annals of Neurology, EarlyView.
Objective Drug‐resistant epilepsy (DRE) remains a clinical challenge, as therapies modifying disease trajectory are lacking. Increasing evidence implicates gut microbiota dysbiosis in epilepsy pathophysiology, with short‐chain fatty acids (SCFAs) emerging as key microbial metabolites with neuroprotective and anti‐inflammatory properties.
Akash A. Bera, Rossella Di Sapia, Greta Volpedo, Sneha Anand, Eray Sahin, Pasquale Baldassarre, Francesca Buffelli, Andrea Petretto, Chiara Lavarello, James D. Mills, Gabriele Cattaneo, Ilaria Craparotta, Eleonora Aronica, Antonella Riva, Pasquale Striano, Annamaria Vezzani, Teresa Ravizza   +16 more
wiley   +1 more source

Immunohistochemical analysis of tumor microvessels.

, 2015
Immunohistochemical detection of endothelial CD31 (A, D, green) and VEGFR-2 (B, E, red) of microvessels within CT26 tumors at day 14 after transplantation of tumor spheroids into the dorsal skinfold chamber of a vehicle-treated control mouse (A-C) and a ...
Matthias W. Laschke (434593), Claudia Scheuer (434594), Julia Parakenings (767357), Christine Wittig (434592), Michael D. Menger (375581)   +4 more
core   +1 more source

Corrigendum: Application of optical tweezers in cardiovascular research: More than just a measuring tool

Frontiers in Bioengineering and Biotechnology, 2022
Yi Yang, Yi Yang, Zhenhai Fu, Wei Zhu, Wei Zhu, Huizhu Hu, Huizhu Hu, Jian’an Wang, Jian’an Wang   +8 more
doaj   +1 more source

Automatic contour extraction from HVEM images of microvessels

, 1992
This work is motivated by the problem raised in the biomedical research utilizing high voltage electron microscope (HVEM) to study microvessels. There, the contour data of cross-sections of microvessels are fed into a special electronic device to ...
Shi, Y. Q., Y. G. Liu, Y. Q. Shi, Engter, P., Liu, Y. G., P. Engter, Horn, L., L. Horn   +7 more
core   +1 more source

ANK1 and EPB41 Variants and the Risk of Steroid‐Induced Osteonecrosis

Arthritis &Rheumatology, EarlyView.
Objective Steroid‐induced osteonecrosis of the femoral head (SONFH) is a refractory skeletal disorder influenced by genetic and environmental factors. However, conclusive pathogenic genetic evidence remains elusive due to the limited exploration of rare damaging variants. In this study, we aimed to identify rare variants associated with SONFH.
Shengbao Chen, Xianmin Zhu, Zhongzhong Chen, Wei Chen, Hussam Alkaissi, Zeng Zhang, Yun Gao, Junhui Yin, Xiangtian Yu, Qiong Fu, Youshui Gao, Zhenzhong Zhu, Qianying Cai, Pengwei Zhang, Weibin Chen, Xin Zhao, Xiaojin Wu, Karel Pacak, Dongxu Jin, Chunde Bao, Zhengping Zhuang, Changqing Zhang   +21 more
wiley   +1 more source

Aryl hydrocarbon receptor-dependent upregulation of Cyp1b1 by TCDD and diesel exhaust particles in rat brain microvessels

Fluids and Barriers of the CNS, 2011
Background AhR activates the transcription of several target genes including CYP1B1. Recently, we showed CYP1B1 as the major cytochrome P450 (CYP) enzyme expressed in human brain microvessels.
Jacob Aude, Hartz Anika MS, Potin Sophie, Coumoul Xavier, Yousif Salah, Scherrmann Jean-Michel, Bauer Björn, Declèves Xavier   +7 more
doaj   +1 more source

A rapid method for isolating rabbit renal microvessels

, 1988
A technique has been described to isolate rabbit renal preglomerular microvessels using an infusion of a magnetized iron oxide suspension into the renal artery.
A. Chaudhari, M. A. Kirschenbaum
core   +1 more source

From anthelmintic to neuro‐oncology: A systematic review of mebendazole repurposing for brain tumour therapy

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Mebendazole (MBZ), a benzimidazole anthelmintic with established clinical use, has emerged as a repurposing candidate for primary brain tumours due to its multimodal anticancer actions and central nervous system penetrance. This systematic review synthesizes preclinical and clinical evidence evaluating MBZ's efficacy, mechanisms of action ...
Ciara B. Blum, Milli McMenamin, Tessa Khoo, John M. Edwin, Prathibha Jose, Liam A. O’Callaghan   +5 more
wiley   +1 more source

Fibronectin promotes the elongation of microvessels during angiogenesis in vitro

, 1993
Fibronectin is a component of the extracellular matrix of developing microvessels whose role in angiogensis is poorly understood. This study evaluated the effect of plasma fibronectin on angiogenesis in serum-free collagen gel culture of rat aorta ...
Elena Bonanno, Nicosia, R, Marion Smith, Roberto F. Nicosia, NICOSIA, RF, SMITH, M., Bonanno, E, BONANNO, ELENA, Smith, M   +8 more
core   +1 more source

Nanomaterial‐based immune therapeutic strategies in neurodegenerative diseases

BMEMat, EarlyView.
This review highlights the immunomodulatory potential of nanomaterials (NMs) in treating neurodegenerative diseases (NDs). It focuses on their roles in regulating innate and adaptive immune responses to maintain immune homeostasis. By providing insights into these mechanisms, the review lays the groundwork for innovative NMs therapeutic strategies to ...
Xinru Zhou, Jia Liu, Shulin Lai, Suhan Yin, Bingmin Luo, Longquan Shao, Yiyuan Kang   +6 more
wiley   +1 more source