Results 141 to 150 of about 46,194 (267)

Women with a history of gestational diabetes mellitus have preserved sensory nerve‐mediated dilatation in the cutaneous microvasculature

Experimental Physiology, EarlyView.
Abstract Women with a history of gestational diabetes mellitus (GDM) have a greater risk of developing type 2 diabetes mellitus and cardiovascular disease than healthy control (HC) women who had an uncomplicated pregnancy. Microvascular endothelial dysfunction, mediated by reduced nitric oxide (NO)‐dependent mechanisms, persists after GDM.
Grace S. Maurer, Kelsey S. Schwartz, Diana I. Jalal, Anna E. Stanhewicz   +3 more
wiley   +1 more source

Zinc Overload in Microvessels Contributes to Blood-Brain Barrier Disruption by Activating the JAK2 Pathway After Cerebral Ischemia/Reperfusion. [PDF]

CNS Neurosci Ther
Guo Z, Shi W, Chen X, Yuan S, Ji X, Qi Z.   +5 more
europepmc   +1 more source

Calcium‐activated chloride channels in pericytes and their role in regulating organ blood flow

The Journal of Physiology, EarlyView.
Abstract figure legend Pericytes are microvascular mural cells with diverse roles. Contractile pericytes directly regulate local perfusion, while non‐contractile pericytes coordinate upstream vascular contractility via propagating electrical signals.
Paolo Tammaro, Hikaru Hashitani
wiley   +1 more source

Mechanisms of Pericyte-Mediated Cancer Metastasis. [PDF]

Adv Sci (Weinh)
Guo Z, Cao Y.
europepmc   +1 more source

Energetic microdomains and the vascular control of neuronal and muscle excitability: Toward a unified model

The Journal of Physiology, EarlyView.
Abstract figure legend The capillary–mitochondria–ion channel (CMIC) axis scales structural resources to match functional workload. (Left) In settings of restricted energetic capacity (e.g. cortical neurons), sparse capillary networks and modest mitochondrial pools set a lower energetic ceiling, sufficient to support phasic, low‐workload excitability. (
L. Fernando Santana, Scott Earley
wiley   +1 more source

PDCD10-Deficient Tumor Cells Reprogram Angiogenesis Through Paracrine Endothelial Activation and GSC-like Plasticity in GBM. [PDF]

Cells
Chen ZR, Chen Z, Wan XY, Busch MA, Dünker N, Rauschenbach L, Sure U, Zhu Y.   +7 more
europepmc   +1 more source

Hypoxia and the cytoskeleton

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic outlining the activation of hypoxia‐sensitive pathways, the influence of hypoxia and associated pathways on the cytoskeleton, and the impact of these on disease progression. Abstract A highly‐regulated and dynamic cytoskeleton is vital for functional cellular physiology and the maintenance of homeostasis.
Darragh Flood, Cormac T. Taylor
wiley   +1 more source

Roles of Ceramide Glucosyltransferase in Controlling Cerebral Microvascular Endothelial Integrity and Angiogenesis Post-Ischemia/Reperfusion. [PDF]

Transl Stroke Res
Mohamud Yusuf A, Zafar M, Hagemann N, Brockmeier U, Schumacher F, Kleuser B, Tertel T, Giebel B, Gulbins E, Hermann DM.   +9 more
europepmc   +1 more source

Preeclampsia‐derived small extracellular vesicles disrupt blood–brain barrier integrity and activate glial cells in vitro

The Journal of Physiology, EarlyView.
Abstract figure legend This study assessed the impact of plasma‐derived small extracellular vesicles (sEVs) from healthy pregnant women and those diagnosed with late‐onset preeclampsia (PE) on the blood–brain barrier (BBB) integrity and glial cell response. PE patients had higher sEV concentrations than healthy controls.
Julián Henao‐Restrepo, José M. Murrieta‐Coxca, Christian Schmeer, Lingyu Wei, Frank Steiniger, Tanja Groten, Udo R. Markert, Diana M. Morales‐Prieto   +7 more
wiley   +1 more source

Vitamin A Uses Its Superpowers to Combat Vascular Malformations. [PDF]

JACC Basic Transl Sci
Markowska Z, Hirschi KK.
europepmc   +1 more source