Results 181 to 190 of about 46,194 (267)

Sex‐Specific Effects of Dexmedetomidine on Brain Microvascular Endothelial Cell Function After Traumatic Brain Injury in Juvenile Mice

CNS Neuroscience &Therapeutics, Volume 32, Issue 10, October 2026.
Traumatic brain injury (TBI) induces acute, sex‐specific activation of endoplasmic reticulum (ER) stress, inflammatory signaling, and ferroptotic mechanisms within brain microvascular endothelial cells (BMECs). Administration of dexmedetomidine (DEX) produces both sex‐dependent and sex‐independent modulatory effects on BMECs, prominently suppressing ...
Yara Mashal, Jie Fan, Tia Atoui, Zahrah Naseer, Sara Moughni, Iman Tawil, Zhi Zhang   +6 more
wiley   +1 more source

Correction to "Shenlian Extract Decreases Mitochondrial Autophagy to Regulate Mitochondrial Function in Microvascular to Alleviate Coronary Artery No-Reflow". [PDF]

Phytother Res
europepmc   +1 more source

ETS-guided iPSC-endothelial models recapitulate malaria pathogenesis. [PDF]

EMBO Mol Med
Korbmacher F, Long RKM, Fleckenstein H, Poliński P, Crusius D, Piatti L, López-Gutiérrez B, Batzilla A, Trivedi V, Ebisuya M, Bernabeu M.   +10 more
europepmc   +1 more source

The endothelium of the pulmonary microvessels.

Journal of Nippon Medical School, 1997
openaire   +3 more sources

Amyloid‐Forming Amylin Secreted by the Pancreas Promotes Hypoxia‐Inducible Factor Activation and Mitochondrial Alterations in Liver and Heart During Type 2 Diabetes Pathogenesis

Comprehensive Physiology, Volume 16, Issue 5, October 2026.
Human amylin is secreted from the pancreas of HIP rats and is amyloidogenic, forming aggregates systemically. In comparison with age‐matched control (WT), hyperglycemic (UCD) and amylin knockout rats (AKO), HIP rats showed increased hypoxia‐inducible factors (HIF‐1/2) in heart and liver, alongside alterations in mitochondrial electron transfer system ...
Alice E. Knapton, Nirmal Verma, Deepak Kotiya, Alice P. Sowton, Benjamin D. Thackray, Lorenz M. W. Holzner, Paula M. Darwin, Sanda Despa, Florin Despa, Andrew J. Murray   +9 more
wiley   +1 more source

Mutations associated with Alzheimer's disease and aged serum synergistically elicit blood-brain barrier dysfunction in a tissue-engineered model. [PDF]

Fluids Barriers CNS
Chung TD, Liang L, Wang L, Kim EG, Gupta S, Pandey I, Searson PC.   +6 more
europepmc   +1 more source

CLDN18.2 in pancreatic ductal adenocarcinoma: Biomarker assessment, spatial heterogeneity and therapeutic modality selection

Clinical and Translational Discovery, Volume 6, Issue 5, October 2026.
This review presents a framework for selecting Claudin 18.2 (CLDN18.2)‐directed treatment modalities in pancreatic ductal adenocarcinoma according to tumour antigen coverage and spatial distribution. Representative assessment at baseline and reassessment after progression can guide treatment adaptation over time.
Ruyu Tan, Zhexin Zhang, Jiaxin Wang, Roland Andersson, Daniel Ansari, Jinfei Chen   +5 more
wiley   +1 more source

Is Imaging of a Single Vessel Sufficient to Assess Pan-Coronary Vulnerability? [PDF]

Catheter Cardiovasc Interv
Scalamera R, Andreaggi S, Kim S, Lee H, McNulty I, Benenati S, Vergallo R, Porto I, Jang IK.   +8 more
europepmc   +1 more source

Multi‐omics integration and machine learning identify an ACKR1+ endothelial cell‐based lactate‐immune signature associated with carotid plaque vulnerability and progression

Clinical and Translational Medicine, Volume 16, Issue 10, October 2026.
ACKR1+ endothelial cells mark intraplaque neovessels with hyperactive glycolysis and lactate metabolism. Lactate, HIF‐1α and CXCL12 link this state to CXCR4+ CD8+ T‐cell recruitment in situ. SLC16A3 and SLC16A4 serve as quantitative readouts of this lactate–immune state.
Ji Zhang, Qijian Zhao, Yufei Wu, Keqiang Shu, Junye Chen, Kang Li, Yuyao Feng, Xu Zhang, Wenjian Liu, Zhichao Lai, Bao Liu   +10 more
wiley   +1 more source

Preliminary Observations of Spatial Imbalance between Lymphangiogenesis and Angiogenesis within Carotid Atherosclerotic Plaques: A Pilot Histopathological Study. [PDF]

Ann Vasc Dis
Tateishi Y, Otsuka H, Torimura D, Yamashita A, Tomita Y, Hirayama T, Shima T, Yoshimura S, Miyazaki T, Ideguchi R, Matsunaga Y, Maeda H, Fukuoka J, Morofuji Y, Izumo T, Tsujino A.   +15 more
europepmc   +1 more source