Clinicopathological features of non-cirrhotic portal fibrosis in primary biliary cholangitis: a 15-year experience at a tertiary referral center. [PDF]
Wang X +5 more
europepmc +1 more source
Disrupted transporter protein expression and cell-specific localization reveal neurovascular unit remodeling in human glioblastoma. [PDF]
Bao X, Jiang Y, Hermes B, Sanai N, Li J.
europepmc +1 more source
Abstract Gastric signet ring cell carcinoma (GSRCC) is a special type of gastric cancer common in young women. Diffuse gastric cancer (DGC) begins with intramucosal lesions comprising differentiated GSRCC cells. Genetically, GSRCC and DGC are clonally identical, with their morphology influenced by extracellular Wnt signaling.
Qian Wang +5 more
wiley +1 more source
Human Brain Vasculature-on-a-Chip Model Constructed With Microvessels Isolated From Cryopreserved Postmortem Human Brain Tissue. [PDF]
O'Grady BJ +5 more
europepmc +1 more source
Ischemia–Reperfusion Injury: Molecular Mechanisms and Therapeutic Interventions
Multiorgan ischemia–reperfusion injury begins with ischemia‐induced ATP depletion and ionic imbalance, followed by reperfusion‐triggered mitochondrial ROS/RNS bursts, regulated cell death, and DAMP release. Sterile inflammation converges on endothelial–immune–coagulation crosstalk, where NETs drive immunothrombosis, no‐reflow, and remote organ injury ...
Peng An +4 more
wiley +1 more source
Retraction: PKCε activation restores loss of PKCε, manganese superoxide dismutase, vascular endothelial growth factor, and microvessels in aged and Alzheimer's disease hippocampus. [PDF]
Frontiers Editorial Office.
europepmc +1 more source
ABSTRACT Snakebite envenomation is a major public health concern, particularly in low‐ and middle‐income regions where access to safe and effective antivenoms is limited. Traditional antivenoms, derived from immunization with crude venom, often trigger adverse reactions and lack specificity against key venom components.
Hanan Maoz, Amir Elalouf
wiley +1 more source
Diabetic cerebral microvascular disorder: from key pathologies to targeted interventions. [PDF]
Zhang Q, Liu J, Ji X.
europepmc +1 more source
Amyloid‐β aggregates induce vasculopathy via ferroptosis in brain endothelial cells
Blood–brain barrier (BBB) disruption is evident in brains with amyloidopathy. In this study, we demonstrate that amyloid β (Aβ) drives abnormal lipid metabolism and lipid droplet formation in brain endothelial cells, leading to lipid peroxidation and ferroptosis.
Suhyeon Son +7 more
wiley +1 more source
Mapping the expression of endothelial adhesion receptors for Plasmodium falciparum-infected erythrocytes in fatal cerebral malaria in Malawian children. [PDF]
Dorovini-Zis K +5 more
europepmc +1 more source

