Results 231 to 240 of about 51,554 (307)

Integrin α5β1‐mediated multicellular crosstalk in the tumor microenvironment drives bladder cancer progression and reveals targetable vulnerabilities

iMetaOmics, Volume 3, Issue 2, June 2026.
Integrating multiplexed immunofluorescence, animal models, and clinical samples, our single‐cell and spatial atlas maps tumor microenvironment evolution during bladder cancer (BCa) progression. We reveal that stemness‐associated tumor cells (SDC1+), POSTN+ myofibroblastic cancer‐associated fibroblasts (mCAFs), and immunosuppressive monocytic myeloid ...
Ting Liang, Wuwu Xu, Hu Fang, Lu Fu, Dashi Deng, Chenchen Li, Lisha Liu, Dongdong Tang, Huancheng Yang, Fang Liu, Xing Xiong, Guangzhi Li, Song Wu, Tao Tao   +13 more
wiley   +1 more source

BBB dynamics: the lifespan perspective. [PDF]

Sci Rep
Ren XS.
europepmc   +1 more source

The Role of Endothelin‐1 in Autoimmune Diseases: Mechanistic Insights and Therapeutic Targets

iNew Medicine, Volume 2, Issue 2, June 2026.
The Role of Endothelin‐1 in Autoimmune Diseases. NF‐κB: nuclear factor kappa‐B; MAPK: mitogen‐activated protein kinase; PI3K: phosphoinositide 3‐kinase; ROS: reactive oxygen species; CTGF: connective tissue growth factor; TGF‐β: transforming growth factor‐β.
Xun Gong, Zhenyu Wang, Suyin Yang, Kaige Gao, Xin Yang, Min Tang   +5 more
wiley   +1 more source

Electroacupuncture alleviates cognitive impairment in mice with vascular dementia by regulating the cholinergic vasodilation system. [PDF]

Front Aging Neurosci
Gao Y, Zhao J, Chen J, Qi R, Yuan Y, Liu B, Yu X, Liu Y.   +7 more
europepmc   +1 more source

Comparison of the SMI Technique and CEUS for the Assessment of Microvasculature in Leiomyosarcoma and Its Clinical Value for Application

Journal of Clinical Ultrasound, Volume 54, Issue 5, Page 1079-1087, June 2026.
SMI and CEUS can clearly reflect the microvascular situation in fibroids and effectively guide the clinical treatment of patients with uterine fibroids, but the effect of SMI is better than that of CEUS in guiding the treatment of patients, which can provide a reference for the selection of clinical treatment programs.
Qiufeng Li, Junbin Du
wiley   +1 more source

High-resolution three-dimensional quantitative photoacoustic and ultrasound imaging of subcutaneous microvasculature in extremities. [PDF]

Biomed Opt Express
Long X, Huang X, Yang M, Emelianov S, Li C.   +4 more
europepmc   +1 more source

The endothelium of the pulmonary microvessels.

Journal of Nippon Medical School, 1997
openaire   +3 more sources

Targeted Delivery of mRNA to the Heart via Extracellular Vesicles or Lipid Nanoparticles

Journal of Extracellular Vesicles, Volume 15, Issue 6, June 2026.
ABSTRACT Efficient and specific delivery of mRNA to target tissues is critical for maximising therapeutic benefits while minimising off‐target effects and systemic toxicity. Systemic administration of mRNA using lipid nanoparticles (LNPs) or extracellular vesicles (EVs) typically leads to predominant accumulation in the liver.
Muhammad Nawaz, Benyapa Tangruksa, Sepideh Heydarkhan‐Hagvall, Franziska Kohl, Hernán González‐King Garibotti, Yujia Jing, Zahra Payandeh, Azadeh Reyahi, Karin Jennbacken, John Wiseman, Leif Hultin, Lennart Lindfors, Jane Synnergren, Hadi Valadi   +13 more
wiley   +1 more source

Limited Microvascular Remodelling Occurs in the Aged Human Hippocampus in Obstructive Sleep Apnoea. [PDF]

Int J Mol Sci
Xu C, Owen JE, Gislason T, Benediktsdottir B, Ye J, Robinson SR.   +5 more
europepmc   +1 more source

Characterizing the Fate of Anti‐CS1 Nanobody Displaying Extracellular Vesicles in Multiple Myeloma

Journal of Extracellular Vesicles, Volume 15, Issue 6, June 2026.
ABSTRACT Extracellular vesicles (EVs) are promising delivery vehicles capable of transporting therapeutic agents across biological barriers. However, native EVs primarily accumulate in liver, spleen and lungs, limiting targeted delivery to disease sites.
Michiel De Coster, Lukas Hyka, Sophie De Cock, Sofie Meeussen, Zuowei Wang, Chenggong Tu, Sophie Hernot, Nick Devoogdt, Guido David, Kim De Veirman, Karin Vanderkerken, Eline Menu, Pascale Zimmermann, Elke De Bruyne   +13 more
wiley   +1 more source