Results 51 to 60 of about 51,554 (307)
Advanced Science, EarlyView.Our study reveals the protective role of GPR124 in maintaining BBB integrity and promoting neurological recovery following TBI. It makes a significant contribution by uncovering a novel molecular interaction between GPR124 and FGFBP1 and linking this to activation of the Wnt/β‐catenin signaling pathway in vascular repair mechanisms.
Chen Wang +13 more
wiley +1 more source
Patterned vascularization in a directional ice‐templated scaffold of decellularized matrix
Engineering in Life Sciences, 2021 Vascularization is fundamental for large‐scale tissue engineering. Most of the current vascularization strategies including microfluidics and three‐dimensional (3D) printing aim to precisely fabricate microchannels for individual microvessels.
Li Shen +9 more
doaj +1 more source
Structure‐Based Algorithms for Microvessel Classification [PDF]
Microcirculation, 2015 AbstractObjectiveRecent developments in high‐resolution imaging techniques have enabled digital reconstruction of three‐dimensional sections of microvascular networks down to the capillary scale. To better interpret these large data sets, our goal is to distinguish branching trees of arterioles and venules from capillaries.MethodsTwo novel algorithms ...
Amy F. Smith +4 more
openaire +4 more sources
Identification of the insulin receptor of cerebral microvessels
, 1985 Cerebral microvessels are known to possess receptors for insulin and have recently been shown to respond to physiological levels of this hormone. Scatchard analysis of binding data obtained with isolated cerebral microvessels gave curvilinear plots and ...
E. Meezan, D. J. Pillion, J. F. Haskell
core +1 more source
Advanced Science, EarlyView.Perivascular matrix densification promotes the emergence of aberrant endothelial tip cells (ATECs) that invade and persist within fibrotic microenvironments. Using in vivo lineage tracing and a human microvessel model, this study shows that fibrous matrix cues destabilize VE‐cadherin–mediated junctions to gate TGF‐β signaling, inducing a pro ...
Jingyi Xia +17 more
wiley +1 more source
Frontiers in Bioengineering and BiotechnologyThe intervertebral disc (IVD) is the largest avascular structure in the human body. The cartilaginous endplate (CEP) is a layer of translucent cartilage located at the upper and lower edges of the vertebral bodies.
Yu Sun +7 more
doaj +1 more source
Frontiers in Neurology, 2020 Background: Cerebral small vessel disease is the most common cause of subcortical vascular dementia (SVaD). Unfortunately, conventional imaging techniques do not always demonstrate the microvascular pathology that is associated with small vessel disease.
Hyeon-Il Choi +5 more
doaj +1 more source
Vasomotor properties of porcine endocardial and epicardial microvessels
, 1992 We sought to compare the sensitivity of endocardial and epicardial microvessels to several important neurohumoral substances. Porcine endocardial microvessels (86-200 microns diam) from the anterior papillary muscle and epicardial microvessels of ...
J. E. Quillen, D. G. Harrison
core +1 more source
Combating VEGFA‐siRNA‐Induced Metabolic Reprogramming via Glucose Utilization Deprivation
Advanced Science, EarlyView.An ionizable lipid nanoparticle co‐delivers VEGFA siRNA and glucose oxidase to tumors to counteract VEGFA knockdown‐induced, glutamine‐driven metabolic compensation. Enzymatic glucose consumption reverses the adaptive pathways and restores metabolism toward baseline, thereby sensitizing tumors to therapy.
Lulu Zheng +10 more
wiley +1 more source
Numbers of microvessels at each time point.
, 2013 Numbers of microvessels at each time point.
Lin Feng (84785) +7 more
core +1 more source