Results 91 to 100 of about 53,608 (248)

Long‐Term Outcomes of Sacral Neuromodulation Explantation: A 12‐Year Experience at a High‐Volume Tertiary Center

Neurourology and Urodynamics, EarlyView.
ABSTRACT Introduction Sacral neuromodulation (SNM) is a therapeutic option offered to patients with idiopathic overactive bladder (OAB) or non‐obstructive urinary retention, as an alternative treatment for refractory medical management. It allows for electrical stimulation of inhibitory circuits that modulate the micturition reflex and improve lower ...
Carly Fiorido, Mario Henrique Bitar Siqueira, Mohammed Aldoukhi, Nojoud Alamri, Eviatar Fields, Naeem Bhojani, Bilal Chughtai, Omar Buksh, Sagi Shprits, Katherine Lajkosz, Dean Elterman   +10 more
wiley   +1 more source

Diabetes‐Induced Dysregulation of Purinergic Signaling in the Bladder Mucosa: Accelerated ATP Hydrolysis and Impaired Adenosine Uptake Promote Underactive Bladder Phenotype

Neurourology and Urodynamics, EarlyView.
ABSTRACT Objective To explore molecular mechanisms underlying excessive extracellular adenosine (ADO) accumulation in the bladder lamina propria (LP) of mice with type 2 diabetes (T2D) induced by a high‐fat, high‐sucrose diet (HFHSD), conceivably leading to bladder underactivity.
Mahsa Borhani Peikani, Brian A. Perrino, Violeta N. Mutafova‐Yambolieva   +2 more
wiley   +1 more source

The Benefits of Adding Non‐Antimuscarinic Pharmaceuticals in Combination With Beta‐3 Agonists for Overactive Bladder Treatment: A Systematic Review

Neurourology and Urodynamics, EarlyView.
ABSTRACT Introduction Antimuscarinics, as the current first‐line pharmacologic therapies for overactive bladder, exhibit low patient adherence and high rates of reported side effects. As a modern alternative pharmaceutical treatment, beta‐3 agonists, which relax the urinary bladder, may be more tolerable for patients, increasing adherence and ...
Felicity Smith, Charlotte Phelps, Christian Moro   +2 more
wiley   +1 more source

A PET study on brain control of micturition in humans

, 1997
Although the brain plays a crucial role in the control of micturition, little is known about the structures involved. Identification of these areas is important because their dysfunction is thought to cause urge incontinence, a major problem in the ...
Willemsen, ATM, Holstege, G, Blok, BFM
core   +1 more source

Voluntary Versus Reflex micturition Control

, 2023
The functions of the lower urinary tract to store and periodically eliminate urine are regulated by a complex neural control system in the brain, spinal cord, and peripheral autonomic ganglia that coordinate the activity of smooth and striated muscles of
Yoshimura, Naoki, Osawa, Teruyuki, de Groat, William C, Kitta, Takeya, Chancellor, Michael B   +4 more
core  

Functional Roles of Adenosine A2B and A3 Receptor Subtypes in the Bladder of Male Rats With A2B Receptor Deletion or Bladder Outlet Obstruction

Neurourology and Urodynamics, EarlyView.
ABSTRACT Purpose To investigate the adenosine receptor (AR) mechanism underlying bladder outlet obstruction (BOO)‐related bladder dysfunction, we examined the expression level of AR subtypes in bladder tissues, and the effects of AR subtypes A2B & A3 modulation on bladder activity using male BOO rats, and Dahl rats with A2B receptor deletion. Materials
Masahiro Kurobe, Ei‐ichiro Takaoka, Kanako Matsuoka, Shingo Kimura, Anne M. Robertson, Edwin K. Jackson, Lori A. Birder, Minoru Miyazato, Naoki Yoshimura   +8 more
wiley   +1 more source

Surgical Treatment of Pelvic Organ Prolapse and Overactive Bladder: A Systematic Review and Meta‐Analysis

Neurourology and Urodynamics, EarlyView.
ABSTRACT Background Pelvic organ prolapse (POP) frequently coexists with overactive bladder (OAB) symptoms, yet the impact of surgical correction on OAB outcomes remains incompletely characterized across different surgical approaches. Objectives To quantify OAB symptom resolution rates following POP surgery, compare outcomes across surgical techniques,
Lorenzo Vacca, Daniela Caramazza, Michele Pierro, Aniello Foresta, Andrea Lombisani, Anna Fagotti, Alfredo Ercoli, Giuseppe Campagna   +7 more
wiley   +1 more source

Association Between Toilet Training Timing and Prognosis of Nocturnal Enuresis in Children: A Retrospective Study

Neurourology and Urodynamics, EarlyView.
ABSTRACT Aims Toilet training (TT) is a critical developmental milestone with potential implications for lower urinary tract function. However, its association with the prognosis of nocturnal enuresis (NE) remains unclear. We aimed to evaluate whether the timing of TT initiation and completion affects 1‐year treatment outcomes in children with NE ...
Shota Endo, Hirokazu Ikeda, Yuma Iwanaka, Takahiro Ono, Chisato Oyake, Yuta Onuki, Yoshitaka Watanabe, Masaki Fuyama, Tsuneki Watanabe   +8 more
wiley   +1 more source

Targeting NADPH Oxidase as an Approach for Diabetic Bladder Dysfunction

Antioxidants
Diabetic bladder dysfunction (DBD) is the most prevalent complication of diabetes mellitus (DM), affecting >50% of all patients. Currently, no specific treatment is available for this condition.
Tammyris Helena Rebecchi Silveira, Fábio Henrique Silva, Warren G. Hill, Edson Antunes, Mariana G. de Oliveira   +4 more
doaj   +1 more source

Adoptive transfer of EAC micturition phenotype.

, 2013
(A–D) Ten days after immunization of mice with UPK3A 65–84 peptide or OVA, CD4+ and CD8+ T cells were isolated, activated with immunogen, and transferred into naïve female BALB/c recipients by i.v. injection.
Vincent K. Tuohy (447058), Fuat Bicer (447056), Cagri Sakalar (257421), Kenan Izgi (447054), Xiaoxia Li (209011), Cengiz Z. Altuntas (447055), Firouz Daneshgari (447059), Ahmet Ozer (447057)   +7 more
core   +1 more source