Results 121 to 130 of about 79,032 (289)
Referent and raw simulated profiles for midazolam.
, 2018 Graphed are mean (±1 SD) midazolam concentration profile from the referent clinical bioequivalence study, and the simulated mean midazolam concentration profile from the ISDAT.
Anika Jhandey (5706785) +6 more
core +1 more source
Classifying seizures in practice: Testing the 2025 ILAE framework among clinicians in South Africa
Epilepsia, EarlyView.Abstract Objective The 2025 International League Against Epilepsy (ILAE) seizure classification introduced a basic version for nonspecialists, but its usability is untested. We evaluated whether a multidisciplinary frontline workforce in South Africa could apply it, how consistently, and whether performance improved after self‐directed exposure ...
Aayesha J. Soni +13 more
wiley +1 more source
Epilepsia, EarlyView.Abstract Objective Magnetoencephalography (MEG) language mapping in pediatric epilepsy frequently requires sedation, which may alter cortical physiology and compromise the reliability of language lateralization. We hypothesized that sedation disrupts coupling between early auditory processing and higher order language networks, reducing the ...
Tao Song +6 more
wiley +1 more source
Midazolam premedication in paediatric anaesthesia [PDF]
, 1986 CITATION: Payne, K. A. et al. 1986. Midazolam premedication in paediatric anaesthesia. South African Medical Journal, 70:657-659.The original publication is available at http://www.samj.org.zaTo investigate the efficacy of midazolam (Dormicum; Roche) as ...
Samuels, G. +3 more
core
An algorithm for seizure detection in rodents
Epilepsia Open, EarlyView.Abstract Objective Epilepsy animal research often relies on long‐term intracranial electroencephalographic (iEEG) recordings. Here, we describe an artificial neural network (ANN) algorithm for automatic detection of seizures. Methods The algorithm was trained on iEEG recordings of three mouse models of chronic epilepsy: (1) the pilocarpine model of ...
Lyna Kamintsky +9 more
wiley +1 more source
PKPD rabbit midazolam-flumazenil
These data are from a PKPD study of midazolam and flumazenil in adult ...
Pang, Daniel
core +1 more source
Neonatal seizures: Advances in diagnosis and management
Epilepsia Open, EarlyView.Abstract The International League Against Epilepsy (ILAE) created the ILAE Neonatal Task Force that classified neonatal seizures, defined neonatal epilepsy syndromes, and specified treatment guidelines. These frameworks, in addition to improved access to genetic testing and other recent advances, have revolutionized the diagnosis and management of ...
Elissa G. Yozawitz +2 more
wiley +1 more source
Status epilepticus: Updates on mechanisms and treatments
Epilepsia Open, EarlyView.Abstract Status epilepticus (SE) consists of prolonged, self‐sustaining seizures and is a common neurological emergency that causes respiratory compromise and neuronal injury. Without prompt treatment, the seizures can become resistant to benzodiazepines, leading to the progressive evolution of established, refractory, and super‐refractory SE.
Suchitra Joshi, Jaideep Kapur
wiley +1 more source
, 1997 In this study we examined the effectiveness midazolam-ketamin combination, midazolam and diazepam in premedication of children and evaluated the effects on hemodynamic and respiratory parameters.
GÖKMEN, ALİ NECATİ +5 more
core +1 more source
Neonatal seizures and GABAergic drugs: Scylla and Charybdis?
Epilepsia Open, EarlyView.Abstract Neonates have a high incidence of seizures that are frequently difficult to control with conventional first‐line anti‐seizure medications, which are gamma‐aminobutyric acid (GABA) agonists. The reasons for this clinical problem are multifold but are likely related to the unique physiology of the immature nervous system. Specifically, the early
Kerry W. Thompson +2 more
wiley +1 more source