Results 151 to 160 of about 145,146 (385)
Clinical Pharmacology &Therapeutics, EarlyView.Atazanavir has been reported to increase total serum bilirubin level up to ninefold. It is widely believed that the observed total bilirubin elevation is primarily due to UGT1A1 inhibition. However, UGT enzymes are well‐known as a low‐affinity and high‐capacity system, and the observed drug–drug interaction mediated by UGTs is usually less than twofold.
Jin Dong +8 more
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Cardiovascular Effects of Sedative Infusions of Propofol and Midazolam after Spinal Anaesthesia [PDF]
, 1988 D. W. Blake +3 more
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Clinical Pharmacology &Therapeutics, EarlyView.The use of elexacaftor/tezacaftor/ivacaftor (ETI) has been associated with increased fertility in women with cystic fibrosis (CF) and is increasingly used during pregnancy to support both maternal and fetal health. However, little is known about the pharmacokinetics (PK) of ETI during pregnancy, which is crucial for optimizing its efficacy and safety ...
Eunjin Hong +8 more
wiley +1 more source
Midazolam: sleep and performance studies in middle age. [PDF]
, 1983 AN Nicholson, BM Stone
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International Journal of Circuit Theory and Applications, EarlyView.This study focused on reducing the simulation counts required for circuit sizing by optimizing the initial population selection in evolutionary algorithms. We investigated the impact of different sampling methods on the efficiency of multi‐objective optimization based on differential evolution and Bayesian inference, a leading algorithm in circuit ...
Georgian Nicolae +5 more
wiley +1 more source
Management of paediatric procedure-related cancer pain
, 1999 Paediatric malignancy is not always painful in its own right; however, young patients with cancer undergo numerous painful procedures for diagnosis, therapy and supportive care, including lumbar puncture, bone marrow aspiration and biopsy.
Liossi, C.
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Double-Blind Comparison of Midazolam and Temazepam as Oral Premedicants for Outpatient Anaesthesia [PDF]
, 1989 Timothy G. Short, D. C. Galletly
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Drug Testing and Analysis, EarlyView.In forensic bioanalysis, often multianalyte approaches are used given their increased effectiveness but can be difficult to develop and maintain in the laboratory, for example, in terms of calibrator solution preparation. A fast, simple, and robust liquid chromatography–tandem mass spectrometry (LC–MS/MS) method for the quantification of 82 classic ...
Andrea E. Steuer +3 more
wiley +1 more source
Alcohol Withdrawal – Therapeutical Management in Surgical Patients with Upper Intestinal Bleeding [PDF]
, 2015 Psychological dependence involves a desire to use a drug to avoid the unpleasant withdrawal syndrome that results from cessation of exposure to it. Alcohol withdrawal syndrome is one of the most feared complications of alcohol addiction and sometimes can
Bogdan, Popescu +5 more
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Drug Testing and Analysis, EarlyView.Simultaneous qualitative and quantitative analysis of 62 drugs and seven active metabolites in human blood plasma by automated liquid chromatography linear ion trap mass spectrometry. ABSTRACT Rapid and comprehensive qualitative and quantitative analytical procedures are crucial in 24/7 emergency toxicology (ET) to support diagnosis and treatment of ...
Selina Hemmer +4 more
wiley +1 more source